{"id":"W4200438338","doi":"10.1093/ofid/ofab466.1244","title":"1050. Phase 3 Trial to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by 23valent Pneumococcal Polysaccharide Vaccine 6 Months Later in At-risk Adults Aged 18–49 Years (PNEU-DAY): A Subgroup Analysis by Baseline Risk Factors","year":2021,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Pneumococcal polysaccharide vaccine; Tolerability; Pneumococcal conjugate vaccine; Immunogenicity; Adverse effect; Vaccination; Internal medicine; Pneumococcal vaccine; Streptococcus pneumoniae; Immunology; Pediatrics; Pneumococcal disease; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00203873,0.001286603,0.002714656,0.0003238178,0.0003731998,0.000917376,0.0007128093,0.001126931,0.003273653],"category_scores_gemma":[0.001358597,0.0005005298,0.003213804,0.0003929902,0.0004683022,0.0007306951,0.0003095519,0.0020959,0.0006034249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007655914,"about_ca_system_score_gemma":0.001156803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001035276,"about_ca_topic_score_gemma":0.002467168,"domain_scores_codex":[0.999292,0.0003940703,0.00004313932,0.0001219764,0.00003772606,0.000111074],"domain_scores_gemma":[0.9992929,0.0001744212,0.000157796,0.00007417832,0.00005992255,0.0002407933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.973713,0.004204492,0.003460482,0.0004115753,0.002643356,0.00006203099,0.00005166396,0.0004239148,0.002627513,0.00007643269,0.0006772393,0.01164826],"study_design_scores_gemma":[0.7680894,0.2144535,0.01260291,0.00005659561,0.002056789,0.00009340013,0.00004759969,0.0008610617,0.0006207279,0.0002202411,0.0008730319,0.00002471541],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911779,0.003023108,0.000427199,0.0002073359,0.000193297,0.002247893,0.001443221,0.00006474552,0.001215308],"genre_scores_gemma":[0.9918578,0.0008959982,0.0008894936,0.0006127636,0.0001786313,0.002373326,0.002022536,0.00001641865,0.001153061],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003273653,"threshold_uncertainty_score":0.01095152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01033705166377352,"score_gpt":0.3007900164486744,"score_spread":0.2904529647849009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}