{"id":"W4200449260","doi":"10.1039/d1fo02271g","title":"Oxidative stress suppression in <i>C</i>. <i>elegans</i> by peptides from dogfish skin <i>via</i> regulation of transcription factors DAF-16 and HSF-1","year":2021,"lang":"en","type":"article","venue":"Food & Function","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Office of Research Infrastructure Programs, National Institutes of Health; National Natural Science Foundation of China","keywords":"Oxidative stress; Caenorhabditis elegans; Peptide; In vivo; Antioxidant; Biochemistry; Enzyme; Amino acid; Biology; Motility; Oxidative phosphorylation; Molecular biology; Chemistry; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001070087,0.0003881606,0.000149955,0.0001461457,0.000131479,0.0002101907,0.0001907677,0.0002582459,0.0009161382],"category_scores_gemma":[0.00007911419,0.0001411205,0.0002087089,0.00006164237,0.0002023425,0.0001763235,0.0001983311,0.000494885,0.0001406246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00027103,"about_ca_system_score_gemma":0.0001970056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000978153,"about_ca_topic_score_gemma":0.001932067,"domain_scores_codex":[0.9999356,0.000004860196,0.000005560903,0.00002086438,0.00001540461,0.00001761495],"domain_scores_gemma":[0.9999069,0.000009625215,0.0000334221,0.000008416328,0.00001346519,0.00002821852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003608464,0.000005970145,0.00004206313,0.00001012105,0.000001034459,0.00001126437,0.000003164899,0.00001108971,0.9996431,0.00001867343,0.00001063041,0.0002066821],"study_design_scores_gemma":[0.000008378224,0.0001088385,0.003493562,0.00000354956,0.000006142297,0.0000472485,0.0000116347,0.0003439892,0.9953191,0.00001777187,0.0006347185,0.000005089769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973068,0.0002462658,0.001055311,0.00006576592,0.00002594368,0.00001863545,0.0002832945,0.00006365456,0.0009343404],"genre_scores_gemma":[0.9948912,0.0002021495,0.001772221,0.00006086404,0.000004851567,0.00002521555,0.0003551398,0.00003175262,0.002656629],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000978153,"threshold_uncertainty_score":0.003064752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006874680865302956,"score_gpt":0.1982945097374604,"score_spread":0.1914198288721574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}