{"id":"W4200449260","doi":"10.1039/d1fo02271g","title":"Oxidative stress suppression in <i>C</i>. <i>elegans</i> by peptides from dogfish skin <i>via</i> regulation of transcription factors DAF-16 and HSF-1","year":2021,"lang":"en","type":"article","venue":"Food & Function","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Office of Research Infrastructure Programs, National Institutes of Health; National Natural Science Foundation of China","keywords":"Oxidative stress; Caenorhabditis elegans; Peptide; In vivo; Antioxidant; Biochemistry; Enzyme; Amino acid; Biology; Motility; Oxidative phosphorylation; Molecular biology; Chemistry; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001093005,0.0001939262,0.0002229042,0.00005019166,0.00006409214,0.00003058926,0.00006861234,0.0002197188,0.00004193688],"category_scores_gemma":[0.00003750175,0.0001805176,0.00009583779,0.0001589199,0.00006864882,0.00003924506,0.00004657207,0.0001142143,7.461097e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002620078,"about_ca_system_score_gemma":0.0000283452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003694866,"about_ca_topic_score_gemma":0.0009129451,"domain_scores_codex":[0.9986998,0.0001571727,0.0003006996,0.0004840514,0.0001866771,0.0001716377],"domain_scores_gemma":[0.9994076,0.00002388597,0.0001589943,0.0002353806,0.0001187005,0.00005542873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008476865,0.0001608781,0.01619406,0.00002517463,0.00008152983,2.939809e-7,0.0001185013,0.00002474675,0.978808,0.000008750267,0.000398994,0.003331381],"study_design_scores_gemma":[0.0007157756,0.001504891,0.0366146,0.0000622498,0.00005095498,0.000001150779,0.0003758442,0.0000330352,0.9573125,0.000271064,0.002871863,0.0001861105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916863,0.002030232,0.005320207,0.00006541378,0.0001455172,0.0001869678,0.0003672357,0.00001154872,0.0001865205],"genre_scores_gemma":[0.996423,0.0002624964,0.000127043,0.00006827177,0.0001030539,0.00002107752,0.002905579,0.00001874737,0.00007074956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02149554,"threshold_uncertainty_score":0.7361295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006874680865302956,"score_gpt":0.1982945097374604,"score_spread":0.1914198288721574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}