{"id":"W4200463876","doi":"10.1007/978-1-0716-1884-4_14","title":"Generation of CpG-Recoded Zika Virus Vaccine Candidates","year":2021,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Zika virus; Virology; Biology; CpG site; Virus; Genome; Cytosine; DNA; Genetics; Gene; DNA methylation; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002616612,0.0003300432,0.0002804358,0.0002020244,0.0001649092,0.0003568055,0.0004234926,0.0003346341,0.002718696],"category_scores_gemma":[0.0003950706,0.000221821,0.0002581915,0.0001732317,0.0001639864,0.0002234064,0.0003452589,0.0009518325,0.000807454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003276886,"about_ca_system_score_gemma":0.0002955922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003048376,"about_ca_topic_score_gemma":0.0006067291,"domain_scores_codex":[0.9998668,0.00002565921,0.0000112486,0.00002153386,0.00003465169,0.00004002838],"domain_scores_gemma":[0.9998901,0.00001947047,0.00002620029,0.00001528315,0.00002340212,0.00002554101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003063883,0.00008916978,0.0002675127,0.00009258017,0.00001888053,0.0000898425,0.00003811713,0.001349436,0.9891465,0.001338019,0.0002952904,0.006968403],"study_design_scores_gemma":[0.0001227276,0.0008097821,0.0005258088,0.00001472618,0.00003900195,0.0001544561,0.00002897826,0.003566297,0.9853151,0.0002021116,0.009205914,0.00001509962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9539676,0.001121833,0.03873694,0.0002557635,0.0001936442,0.0005727703,0.001180187,0.0002143036,0.003756902],"genre_scores_gemma":[0.9550582,0.000853003,0.03249259,0.0001144203,0.00001548753,0.0002789517,0.001763994,0.00006753574,0.009355941],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.002718696,"threshold_uncertainty_score":0.009094894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03487655126645618,"score_gpt":0.4146938904621444,"score_spread":0.3798173391956882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}