{"id":"W4200464648","doi":"10.1080/2162402x.2021.2010905","title":"CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development","year":2021,"lang":"en","type":"article","venue":"OncoImmunology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research; BC Cancer Foundation; Terry Fox Research Institute","keywords":"CCL5; Tumor microenvironment; Immune system; Cancer research; Chemokine; KRAS; Lung cancer; Immunotherapy; Cytokine; Immunology; Medicine; T cell; CD8; Cancer; Biology; IL-2 receptor; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001903173,0.0001606436,0.0003148063,0.0001135512,0.00006730607,0.00001349538,0.00006481709,0.00007508688,0.0002573332],"category_scores_gemma":[0.00001621454,0.0001535762,0.0000315882,0.0001895415,0.00009023281,0.00006513034,0.00007338233,0.0001669309,0.00001120024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004577108,"about_ca_system_score_gemma":0.0002806652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002652194,"about_ca_topic_score_gemma":0.0005370377,"domain_scores_codex":[0.9987522,0.00007581477,0.0003399173,0.0004344724,0.00009919636,0.0002983482],"domain_scores_gemma":[0.9995287,0.00001095004,0.0000684378,0.0003038331,0.00003518003,0.00005288477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008403811,0.0003182898,0.0132372,0.00008048647,0.0000956059,0.00005134911,0.001993691,0.00000402631,0.9362971,0.000001696073,0.0001292722,0.04695096],"study_design_scores_gemma":[0.001352803,0.0002311178,0.3292337,0.0001809135,0.00002234052,0.0001413281,0.0002864321,0.000006212847,0.6568439,0.000002026412,0.01156274,0.0001365231],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982888,0.01257209,0.00001030632,0.00338127,0.0005391362,0.0005176365,0.000003141282,0.00002521411,0.00006319101],"genre_scores_gemma":[0.9934334,0.001343557,0.002405229,0.0007392223,0.00009515826,0.000181448,0.00003286846,0.00002780183,0.001741352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3159965,"threshold_uncertainty_score":0.6262658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01265049209481667,"score_gpt":0.2743704889463154,"score_spread":0.2617199968514988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}