{"id":"W4200500950","doi":"10.1093/sleep/zsab290","title":"Combined intermittent and sustained hypoxia is a novel and deleterious cardio-metabolic phenotype","year":2021,"lang":"en","type":"article","venue":"SLEEP","topic":"High Altitude and Hypoxia","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; University of California, San Diego; National Institutes of Health; American Academy of Sleep Medicine Foundation; American Thoracic Society","keywords":"Intermittent hypoxia; Hypoxia (environmental); Hypoxemia; Medicine; Internal medicine; Blood pressure; Obstructive sleep apnea; Oxidative stress; Endocrinology; Cardiology; Oxygen; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000979025,0.0003902743,0.0003284061,0.000200586,0.0001994481,0.0002303136,0.0002287803,0.0002848537,0.001198835],"category_scores_gemma":[0.0001090439,0.00009895154,0.0002104145,0.0001444614,0.0003554935,0.0001588971,0.000476507,0.0003939626,0.0001054796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001091672,"about_ca_system_score_gemma":0.000132708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001971694,"about_ca_topic_score_gemma":0.0004029743,"domain_scores_codex":[0.9999073,0.00001138072,0.000007818512,0.00003261074,0.00002025893,0.00002067163],"domain_scores_gemma":[0.9998268,0.00001038541,0.00007358268,0.00001328167,0.00001139207,0.00006451839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002895316,0.0005292481,0.1114633,0.0003142674,0.0001739161,0.008371981,0.0002075576,0.0001752828,0.8574794,0.0005626702,0.0006816529,0.01714545],"study_design_scores_gemma":[0.0001480961,0.005599196,0.8895913,0.00007105911,0.0002289061,0.04153619,0.0004864934,0.00170338,0.0558285,0.0007125044,0.004067329,0.00002698438],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972956,0.0008110928,0.001024523,0.00008925131,0.00002033418,0.00001305236,0.0001344467,0.00002933327,0.0005822531],"genre_scores_gemma":[0.9985356,0.0003729077,0.000386007,0.00004776896,0.00004910454,0.00002154058,0.0001820829,0.000004072142,0.0004009116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001198835,"threshold_uncertainty_score":0.004010499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007214176713849209,"score_gpt":0.2228988072410725,"score_spread":0.2156846305272233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}