{"id":"W4200500950","doi":"10.1093/sleep/zsab290","title":"Combined intermittent and sustained hypoxia is a novel and deleterious cardio-metabolic phenotype","year":2021,"lang":"en","type":"article","venue":"SLEEP","topic":"High Altitude and Hypoxia","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; University of California, San Diego; National Institutes of Health; American Academy of Sleep Medicine Foundation; American Thoracic Society","keywords":"Intermittent hypoxia; Hypoxia (environmental); Hypoxemia; Medicine; Internal medicine; Blood pressure; Obstructive sleep apnea; Oxidative stress; Endocrinology; Cardiology; Oxygen; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005877626,0.0001364339,0.0001823953,0.00002449143,0.00007046765,0.00004525472,0.00006740344,0.00009387916,0.00002068812],"category_scores_gemma":[0.00003546099,0.000133014,0.00005543866,0.00005767707,0.00006375794,0.000003442291,0.0002055696,0.00006394195,0.000005460396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004606112,"about_ca_system_score_gemma":0.00003791819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002072466,"about_ca_topic_score_gemma":0.00002958861,"domain_scores_codex":[0.9992293,0.00002422556,0.0001296149,0.0003308593,0.00007629162,0.0002097583],"domain_scores_gemma":[0.999515,0.000004364651,0.00003167332,0.0002551462,0.00008920459,0.0001045892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001106553,0.00009197876,0.005617328,0.00004410667,0.0002365092,0.00005663496,0.0002839401,0.000001521645,0.9760624,0.0007104446,0.001181437,0.01560301],"study_design_scores_gemma":[0.009685145,0.001057131,0.1976296,0.00004693239,0.0004611875,0.0004602319,0.001023236,0.0004604135,0.3127912,0.0004798468,0.4744991,0.001405937],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992718,0.0053643,0.0006469972,0.0004349632,0.0001177957,0.00009835055,0.00002402123,0.00001091734,0.0005846241],"genre_scores_gemma":[0.9966699,0.0005994606,0.0005862179,0.001213503,0.0001304631,0.000009998415,0.00005742518,0.00001853937,0.0007144946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6632712,"threshold_uncertainty_score":0.5424153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007214176713849209,"score_gpt":0.2228988072410725,"score_spread":0.2156846305272233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}