{"id":"W4200520522","doi":"10.1182/blood-2021-149365","title":"Vincristine Sulfate Liposome Injection (VSLI, Marqibo®) in Combination with UK ALL-R3 Induction Chemotherapy for Children, Adolescents and Young Adults with Relapsed Acute Lymphoblastic Leukemia (ALL): A Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) Consortium Trial","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Vincristine; Tolerability; Regimen; Pharmacology; Chemotherapy regimen; Chemotherapy; Oncology; Internal medicine; Adverse effect; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009728461,0.0006387338,0.0008727143,0.0001949192,0.0002320713,0.0006956752,0.0005576204,0.0006555829,0.002019652],"category_scores_gemma":[0.0005333323,0.0002622251,0.0007198327,0.0002460146,0.0004123106,0.0004407021,0.0003363741,0.00172102,0.0004955938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009783864,"about_ca_system_score_gemma":0.001092991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001238453,"about_ca_topic_score_gemma":0.002754552,"domain_scores_codex":[0.9997054,0.0001620025,0.00001700111,0.00004324999,0.00002960954,0.00004280204],"domain_scores_gemma":[0.9996616,0.00004865645,0.00009497072,0.00002918217,0.00002005828,0.0001455727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7332181,0.04361887,0.0158856,0.001265401,0.001974585,0.0003441359,0.000458706,0.002499385,0.04359211,0.0005433368,0.006167812,0.1504319],"study_design_scores_gemma":[0.5497915,0.4161829,0.02025163,0.00008313082,0.001008995,0.0004500567,0.00008534473,0.001637142,0.005623392,0.0001239612,0.004736191,0.00002576447],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958706,0.001490747,0.0001467687,0.000247751,0.00004507082,0.0007712871,0.0003953142,0.00004904485,0.0009833764],"genre_scores_gemma":[0.9951116,0.001014868,0.0005847181,0.0003071582,0.00005752385,0.0009015058,0.0007118278,0.00001108081,0.001299657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002019652,"threshold_uncertainty_score":0.007098675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00665624975934691,"score_gpt":0.24544850874567,"score_spread":0.2387922589863231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}