{"id":"W4200540326","doi":"10.1016/j.biomaterials.2021.121342","title":"Degradable methacrylic acid-based synthetic hydrogel for subcutaneous islet transplantation","year":2021,"lang":"en","type":"article","venue":"Biomaterials","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Breakthrough T1D Canada; Canadian Institutes of Health Research; Canada First Research Excellence Fund; Juvenile Diabetes Research Foundation United States of America","keywords":"Islet; Transplantation; Self-healing hydrogels; PEG ratio; Subcutaneous injection; Polyethylene glycol; Subcutaneous tissue; Medicine; Biomedical engineering; Materials science; Diabetes mellitus; Chemistry; Surgery; Internal medicine; Endocrinology; Biochemistry; Polymer chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002165918,0.000328263,0.0001475188,0.0002159989,0.0000842914,0.0002106168,0.0001536665,0.0002888082,0.0008359226],"category_scores_gemma":[0.0001323272,0.0001197649,0.0001936965,0.0001234155,0.0001062933,0.0003519407,0.0001685034,0.0002600659,0.0002158337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000138627,"about_ca_system_score_gemma":0.0001475302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001160802,"about_ca_topic_score_gemma":0.0002842539,"domain_scores_codex":[0.9999269,0.000009629778,0.000007309005,0.00001310789,0.00002451253,0.00001845128],"domain_scores_gemma":[0.9999118,0.00001532774,0.00003735723,0.000006796176,0.00000882293,0.00001996286],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007106656,0.00002536234,0.00005809147,0.00006586783,0.000003636039,0.00006318314,0.000007820488,0.000130035,0.9962388,0.00006928809,0.00004501861,0.003221784],"study_design_scores_gemma":[0.00002414655,0.0004249584,0.001224471,0.00001663208,0.00002314025,0.0003361554,0.00001640659,0.001450729,0.9937044,0.00004890173,0.002719953,0.00001022622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9698719,0.01012526,0.01562773,0.0001480606,0.0002436153,0.00009011122,0.0002977102,0.0001698534,0.003425916],"genre_scores_gemma":[0.9865307,0.002125565,0.008641098,0.00007431136,0.00003139794,0.00005237446,0.0001048177,0.00002864901,0.002410955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008359226,"threshold_uncertainty_score":0.002796471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02464302759750632,"score_gpt":0.2726630350719436,"score_spread":0.2480200074744373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}