{"id":"W4200546506","doi":"10.3390/jpm11121323","title":"Dysregulated Notch Signaling in the Airway Epithelium of Children with Wheeze","year":2021,"lang":"en","type":"article","venue":"Journal of Personalized Medicine","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Health and Medical Research Council; Asthma Foundation","keywords":"Wheeze; JAG1; Airway; Medicine; Notch signaling pathway; Asthma; Immunology; Respiratory epithelium; Pathology; Receptor; Internal medicine; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014985,0.0001711622,0.0003688044,0.0004143242,0.0002609845,0.0004466201,0.0001416341,0.0003607389,0.0008743319],"category_scores_gemma":[0.0004562007,0.0001875172,0.000244981,0.0003658599,0.0002625708,0.0002503175,0.0002580844,0.0005122828,0.00017412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003383292,"about_ca_system_score_gemma":0.000253467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002153687,"about_ca_topic_score_gemma":0.002451728,"domain_scores_codex":[0.9997742,0.00002950904,0.00002043845,0.00005266971,0.00007165588,0.00005161002],"domain_scores_gemma":[0.9998305,0.00002862301,0.00006294291,0.00001048618,0.00002631288,0.00004112909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001140075,0.00009137461,0.7882637,0.0001697599,0.00006837119,0.003936971,0.0006642822,0.0001056972,0.1921691,0.0001283655,0.000294892,0.01296746],"study_design_scores_gemma":[0.000007042058,0.0001732536,0.9877214,0.00001375666,0.00003404779,0.00471757,0.0006650588,0.00008758681,0.005922443,0.00003472694,0.0006188141,0.000004309472],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987621,0.0007582913,0.00008281606,0.00003781088,0.000003980421,0.000004607925,0.0001340434,0.000004926164,0.0002114238],"genre_scores_gemma":[0.9987747,0.000598341,0.0001878263,0.00003387074,0.000004089472,0.000007125075,0.0001899315,0.000003772345,0.0002003858],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002153687,"threshold_uncertainty_score":0.004282296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03678726886627507,"score_gpt":0.3523516433079669,"score_spread":0.3155643744416918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}