{"id":"W4205154650","doi":"10.3389/fimmu.2021.785275","title":"N-Formyl Methionine Peptide-Mediated Neutrophil Activation in Systemic Sclerosis","year":2022,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Research Foundation; National Institutes of Health; Scleroderma Foundation; Arthritis National Research Foundation","keywords":"Neutrophil extracellular traps; Calprotectin; Pathogenesis; Immunology; Inflammation; Systemic inflammation; Formyl peptide receptor; Medicine; Receptor; Internal medicine; Disease; Chemotaxis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002578257,0.0001816545,0.0001363042,0.0004115945,0.00008669213,0.0001565189,0.00005902004,0.0001832102,0.000777096],"category_scores_gemma":[0.0003194484,0.00009150447,0.0000820268,0.0001994174,0.0001424745,0.0001111349,0.0001440398,0.0001557561,0.0001141526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009955149,"about_ca_system_score_gemma":0.00007669938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002701227,"about_ca_topic_score_gemma":0.0004133161,"domain_scores_codex":[0.9999056,0.00003933359,0.000008750785,0.00001585338,0.00002330193,0.000007298026],"domain_scores_gemma":[0.9998279,0.00003552025,0.00007969428,0.000008445862,0.00001582941,0.000032505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003031037,0.0002224195,0.5514245,0.0003064151,0.0001368665,0.001842371,0.0003827465,0.0005460404,0.4095968,0.0001183731,0.0003665688,0.03202591],"study_design_scores_gemma":[0.00003431513,0.0009197769,0.9855095,0.00001488236,0.00003698374,0.003469832,0.00008048541,0.0009530732,0.008416094,0.00009261827,0.0004667412,0.00000574142],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989098,0.0007594508,0.0001227053,0.00001075547,0.000001652025,0.00000322691,0.00001560679,0.000005924315,0.0001707612],"genre_scores_gemma":[0.9994192,0.000251189,0.0001660915,0.000008249328,0.000004242071,0.000004243043,0.00003248933,6.609632e-7,0.0001135759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000777096,"threshold_uncertainty_score":0.002599657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01454387955096305,"score_gpt":0.2099106494643523,"score_spread":0.1953667699133893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}