{"id":"W4205167581","doi":"10.3390/toxics10010022","title":"Behavioral Effects of Buspirone in Juvenile Zebrafish of Two Different Genetic Backgrounds","year":2022,"lang":"en","type":"article","venue":"Toxics","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto Mississauga; University of Toronto","keywords":"Buspirone; Zebrafish; Anxiolytic; Thigmotaxis; Pharmacology; Juvenile; Biology; Drug; Endocrinology; Receptor; Genetics; Gene; Agonist","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000133884,0.0005756982,0.0003421494,0.0005132535,0.0003016237,0.0002189547,0.0003051228,0.0004768308,0.00191991],"category_scores_gemma":[0.0001511941,0.0002568612,0.0005503469,0.0001591268,0.0003809464,0.0002960508,0.0002826653,0.001338751,0.0002916555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001009131,"about_ca_system_score_gemma":0.0005713138,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01085055,"about_ca_topic_score_gemma":0.02430741,"domain_scores_codex":[0.9998214,0.00001236599,0.00001957983,0.00004672724,0.000052165,0.00004784858],"domain_scores_gemma":[0.9997906,0.00002231202,0.00006326572,0.00001496303,0.00003520348,0.00007370853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001752424,0.00003574577,0.0002255392,0.00002618721,0.000005443278,0.00006431092,0.00003256854,0.00002955146,0.9989069,0.00004085563,0.00005454064,0.0004029944],"study_design_scores_gemma":[0.0001015562,0.004039434,0.03723998,0.00002582905,0.000103515,0.0002660666,0.0002432496,0.0009357265,0.9547074,0.0001063596,0.00218218,0.00004868612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995464,0.0004591058,0.0007368759,0.0002534429,0.00006301574,0.00005635501,0.001306332,0.00009076698,0.001570133],"genre_scores_gemma":[0.9823293,0.0009683162,0.00319114,0.0003028714,0.00002223321,0.0003221419,0.001612123,0.00006815462,0.01118374],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01085055,"threshold_uncertainty_score":0.0215748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01301849042268447,"score_gpt":0.3033463012899247,"score_spread":0.2903278108672402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}