{"id":"W4205167581","doi":"10.3390/toxics10010022","title":"Behavioral Effects of Buspirone in Juvenile Zebrafish of Two Different Genetic Backgrounds","year":2022,"lang":"en","type":"article","venue":"Toxics","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto Mississauga; University of Toronto","keywords":"Buspirone; Zebrafish; Anxiolytic; Thigmotaxis; Pharmacology; Juvenile; Biology; Drug; Endocrinology; Receptor; Genetics; Gene; Agonist","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001152842,0.00009279438,0.0001767781,0.00007556021,0.00003593304,0.000003706064,0.0003229605,0.00005384195,0.0001212068],"category_scores_gemma":[0.00005550094,0.00009593085,0.00006795892,0.0002177818,0.0001435877,0.000001472421,0.00039909,0.0001424257,0.00000183558],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000385089,"about_ca_system_score_gemma":0.00008260935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000084857,"about_ca_topic_score_gemma":0.0000769772,"domain_scores_codex":[0.9988785,0.00009197478,0.0002698236,0.0002190427,0.0003206028,0.0002200923],"domain_scores_gemma":[0.999384,0.00003315054,0.00008697097,0.0003728953,0.00003380554,0.00008914817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003334027,0.0007446131,0.004846661,0.0000551809,0.00001267824,0.000004471646,0.0000393313,0.0000321418,0.9886461,0.0001120379,0.0008074325,0.004666031],"study_design_scores_gemma":[0.001801505,0.001530766,0.05493634,0.00001418539,0.00002113082,0.000006016574,0.00006733956,0.0001372539,0.9347911,0.0004075682,0.006114836,0.0001719738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985251,0.0003297954,0.0005067496,0.00008979828,0.00005082281,0.0002859961,0.00005362108,0.00000460678,0.0001535225],"genre_scores_gemma":[0.9989188,0.00004443519,0.0004664504,0.00006109871,0.00003626699,0.0001750115,0.0001076076,0.00001660929,0.0001736999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.053855,"threshold_uncertainty_score":0.3911946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01301849042268447,"score_gpt":0.3033463012899247,"score_spread":0.2903278108672402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}