{"id":"W4205169005","doi":"10.1161/atvbaha.121.317335","title":"Apo(a) and ApoB Interact Noncovalently Within Hepatocytes: Implications for Regulation of Lp(a) Levels by Modulation of ApoB Secretion","year":2022,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Apolipoprotein B; Secretion; Biosynthesis; Coupling (piping); Enzyme; Receptor; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001889399,0.0002073451,0.0002195109,0.0001155374,0.0001757245,0.0005296175,0.0002001827,0.000215829,0.0009567336],"category_scores_gemma":[0.0001767595,0.0001580578,0.0002474822,0.0001099462,0.0002904379,0.0002878266,0.0003128886,0.0003030572,0.0006055139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004481769,"about_ca_system_score_gemma":0.0001719897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004683395,"about_ca_topic_score_gemma":0.0003838629,"domain_scores_codex":[0.9997929,0.0000376226,0.00001987429,0.00005348071,0.00005695528,0.00003914908],"domain_scores_gemma":[0.9997972,0.00003264759,0.0000698864,0.00003269888,0.00002612507,0.00004150717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001271297,0.00002021784,0.001646093,0.0000210417,0.000008013942,0.00005075314,0.00001417802,0.00005329231,0.9974089,0.0001017624,0.00001543098,0.000533302],"study_design_scores_gemma":[0.00001640164,0.0002504585,0.01898783,0.000005611778,0.00002590597,0.000396434,0.0000731612,0.001764526,0.9771892,0.0001222776,0.001161295,0.000006935531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968009,0.0006114308,0.001903023,0.00006533078,0.000006623721,0.000007647836,0.00007730989,0.00002355194,0.0005040451],"genre_scores_gemma":[0.99782,0.0002475407,0.001082814,0.00002270757,0.000004962151,0.00001274124,0.0001247995,0.00001241251,0.0006720338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009567336,"threshold_uncertainty_score":0.003251791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05239830854585999,"score_gpt":0.3140502062612091,"score_spread":0.2616518977153491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}