{"id":"W4205306282","doi":"10.3389/fendo.2021.815532","title":"Commentary: In Utero Exposure to Metformin Reduces the Fertility of Male Offspring in Adulthood","year":2022,"lang":"en","type":"letter","venue":"Frontiers in Endocrinology","topic":"Ovarian function and disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fondation Jean-Louis Lévesque","keywords":"Offspring; In utero; Metformin; Fertility; Reproduction; Medicine; Gynecology; Physiology; Pregnancy; Internal medicine; Demography; Endocrinology; Biology; Environmental health; Genetics; Population; Insulin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003373525,0.001420554,0.001599857,0.0007970417,0.002486791,0.001913691,0.002321408,0.03623391,0.01112589],"category_scores_gemma":[0.01827707,0.0006214473,0.001497264,0.0005920409,0.001689206,0.002025072,0.00102268,0.02794783,0.01132327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003088467,"about_ca_system_score_gemma":0.00272655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006136495,"about_ca_topic_score_gemma":0.00687265,"domain_scores_codex":[0.9984675,0.0004068716,0.0001958847,0.0002855259,0.0004870545,0.0001570964],"domain_scores_gemma":[0.993834,0.003360837,0.0004016798,0.000165188,0.001414999,0.0008233159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008920011,0.00002189076,0.000116376,0.00006348635,0.0000117868,0.000426698,0.00003752459,0.00002345673,0.0001205614,0.0004374073,0.9946714,0.003980347],"study_design_scores_gemma":[0.0002196347,0.0001587354,0.001396498,0.0004617573,0.00006154368,0.001208407,0.0001880715,0.0002166199,0.0003518148,0.004209327,0.9914531,0.00007445998],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002658864,0.00194799,0.00009517006,0.9074067,0.08760229,0.00002560263,0.0003364209,0.0000824661,0.002237452],"genre_scores_gemma":[0.001957074,0.001675791,0.0001665847,0.8958729,0.09117723,0.00005833447,0.00008618827,0.00003286585,0.008972955],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03623391,"threshold_uncertainty_score":0.03721982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01550662018754486,"score_gpt":0.2538555366637495,"score_spread":0.2383489164762046,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}