{"id":"W4205329448","doi":"10.3390/vaccines10010124","title":"Immunoprofiling Identifies Functional B and T Cell Subsets Induced by an Attenuated Whole Parasite Malaria Vaccine as Correlates of Sterile Immunity","year":2022,"lang":"en","type":"article","venue":"Vaccines","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Immune system; Malaria vaccine; Malaria; T cell; Immunization; Vaccine efficacy; Immunity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003037505,0.0002131307,0.0002426805,0.00007916691,0.0003333341,0.00005066846,0.000243934,0.000099265,0.0001684157],"category_scores_gemma":[0.00002995376,0.0002067076,0.00006784859,0.0001660845,0.00001310997,0.00003356959,0.0004216077,0.0001928128,0.000006586479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001171552,"about_ca_system_score_gemma":0.00004883587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001962786,"about_ca_topic_score_gemma":0.00001147939,"domain_scores_codex":[0.9988453,0.00009514134,0.0004266837,0.0002606865,0.0001500507,0.000222123],"domain_scores_gemma":[0.9991375,0.00001763379,0.0002485491,0.0004227798,0.0001174718,0.00005606764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000455116,0.0001542662,0.01784894,0.00004761191,0.00008046387,5.84926e-7,0.0002146743,0.0001661867,0.9794647,0.00001359291,0.001240941,0.0003129244],"study_design_scores_gemma":[0.003018984,0.001423531,0.2198063,0.00001715395,0.00009829122,0.000092897,0.004260243,0.002245519,0.7651333,0.0001186707,0.003217012,0.0005681477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968817,0.002244584,0.00004438808,0.00008991415,0.0002528084,0.0002270671,0.0001042159,0.00001866645,0.0001366527],"genre_scores_gemma":[0.996723,0.000129344,0.00007277048,0.00006521421,0.00004461259,0.00004302375,0.002046372,0.00002941684,0.0008462381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2143314,"threshold_uncertainty_score":0.8429291,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01295532935207817,"score_gpt":0.2281837233130921,"score_spread":0.2152283939610139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}