{"id":"W4205329448","doi":"10.3390/vaccines10010124","title":"Immunoprofiling Identifies Functional B and T Cell Subsets Induced by an Attenuated Whole Parasite Malaria Vaccine as Correlates of Sterile Immunity","year":2022,"lang":"en","type":"article","venue":"Vaccines","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Immune system; Malaria vaccine; Malaria; T cell; Immunization; Vaccine efficacy; Immunity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006605816,0.0003982786,0.0005038014,0.0006603937,0.0001875458,0.0007953168,0.0002736207,0.0003055516,0.0008617001],"category_scores_gemma":[0.00146924,0.0001864459,0.0006083994,0.0003756027,0.0002503299,0.0004637431,0.0003801796,0.0005255953,0.0002287606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002507601,"about_ca_system_score_gemma":0.0003774553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006754787,"about_ca_topic_score_gemma":0.0006807827,"domain_scores_codex":[0.9998179,0.0000580711,0.0000132954,0.0000469404,0.00003546688,0.00002823091],"domain_scores_gemma":[0.9994721,0.0002954708,0.00008194613,0.00007076173,0.00004639323,0.00003334136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"observational","study_design_scores_codex":[0.001775835,0.0005011081,0.1460162,0.0006251183,0.0003461782,0.0004004308,0.0003497931,0.3753898,0.350056,0.004319733,0.001553113,0.1186666],"study_design_scores_gemma":[0.00001922287,0.0002986293,0.04304377,0.00002158379,0.00006076807,0.0001605784,0.0001229806,0.9090081,0.04316122,0.003022919,0.001049274,0.00003101546],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9469513,0.0001977027,0.05001965,0.0001240969,0.00001153522,0.0000576549,0.001165271,0.000505663,0.0009670865],"genre_scores_gemma":[0.9706707,0.0001508039,0.02747262,0.00005700566,0.00000542829,0.00008674769,0.00133704,0.00003661901,0.0001831122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008617001,"threshold_uncertainty_score":0.003493547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01295532935207817,"score_gpt":0.2281837233130921,"score_spread":0.2152283939610139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}