{"id":"W4205430186","doi":"10.1016/s1474-4422(21)00463-4","title":"Advances and ongoing research in the treatment of autoimmune neuromuscular junction disorders","year":2022,"lang":"en","type":"review","venue":"The Lancet Neurology","topic":"Myasthenia Gravis and Thymoma","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Leids Universitair Medisch Centrum; Ministry of Health, Labour and Welfare; Japan Blood Products Organization; Alexion Pharmaceuticals; Union Chimique Belge; Guthy-Jackson Charitable Foundation; Multiple Sclerosis Society; Chugai Pharmaceutical; Roche; Bayer Schering; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; Novartis","keywords":"Myasthenia gravis; Medicine; Neuromuscular junction; Weakness; Immunotherapy; Clinical trial; Immunology; Intensive care medicine; Vaccination; Immune system; Neuroscience; Internal medicine; Surgery; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009796717,0.0001926871,0.001207261,0.0001848668,0.0001415363,0.000008798916,0.0002734592,0.00008799358,0.00005256819],"category_scores_gemma":[0.00005363569,0.00009039029,0.0001774798,0.0004532123,0.0002420213,0.000017327,0.00007606391,0.0007543549,0.000004519237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002250654,"about_ca_system_score_gemma":0.00006558608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001267635,"about_ca_topic_score_gemma":0.00006684844,"domain_scores_codex":[0.9969038,0.00187145,0.0003234464,0.0003133921,0.0002675191,0.0003203937],"domain_scores_gemma":[0.9979692,0.001152002,0.0001383082,0.0007097024,0.00001111223,0.00001969903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001418213,0.0001547916,0.0001516332,0.001862422,0.00003613031,0.0000718427,0.0003212979,0.000001502894,6.198176e-7,0.0003986594,0.00004865961,0.9968106],"study_design_scores_gemma":[0.0006090024,0.002544171,0.001614783,0.0001836481,0.0001978199,0.0003044052,0.00003635216,0.00001204829,6.206981e-8,0.0004472586,0.9939941,0.00005638468],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00424879,0.9893541,5.30839e-7,0.003711506,0.0002095829,0.001129842,0.00000551873,0.00001348165,0.001326659],"genre_scores_gemma":[0.001120227,0.9980389,0.000003511547,0.0002246203,0.0001970329,0.0003104879,0.00002724326,0.0000271508,0.00005075739],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9967542,"threshold_uncertainty_score":0.3686009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1760126315961933,"score_gpt":0.4242586232831688,"score_spread":0.2482459916869756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}