{"id":"W4205450923","doi":"10.1182/blood.v130.suppl_1.821.821","title":"A Phase Ib/IIa Trial of the Combination of Romidepsin, Lenalidomide and Carfilzomib in Patients with Relapsed/Refractory Lymphoma Shows Complete Responses in Relapsed and Refractory B- and T-Cell Lymphomas","year":2017,"lang":"en","type":"article","venue":"Blood","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Carfilzomib; Lenalidomide; Refractory (planetary science); Medicine; Romidepsin; Lymphoma; Internal medicine; Oncology; Multiple myeloma; Materials science; Chemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001708853,0.00158381,0.001832575,0.0004374549,0.0003901809,0.0008600221,0.0007352452,0.0009861153,0.002571199],"category_scores_gemma":[0.0005858003,0.0005445183,0.0009323281,0.0003654633,0.0008420175,0.0004710563,0.0002320129,0.002824822,0.0007702432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007782317,"about_ca_system_score_gemma":0.001045509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006828906,"about_ca_topic_score_gemma":0.001954583,"domain_scores_codex":[0.999506,0.0002661473,0.00002786784,0.00007234408,0.00004253315,0.00008511073],"domain_scores_gemma":[0.9994735,0.00009823295,0.00008523077,0.0000473312,0.00002623384,0.0002695774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6828505,0.07254747,0.01197972,0.001110622,0.002199643,0.0007858574,0.0004456869,0.002736558,0.09124687,0.000314643,0.007271553,0.1265109],"study_design_scores_gemma":[0.6120635,0.3573804,0.01796072,0.00004497103,0.0005468635,0.000660523,0.00005242445,0.001162406,0.007159136,0.0001195418,0.002819826,0.00002974272],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918804,0.002649333,0.0003667107,0.0004898045,0.00009283242,0.001557519,0.0006416109,0.000103075,0.002218685],"genre_scores_gemma":[0.992395,0.00116403,0.001125647,0.000546314,0.0001641412,0.001068997,0.001701902,0.000024485,0.001809546],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002571199,"threshold_uncertainty_score":0.009037375,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01105030261287999,"score_gpt":0.2346118855653973,"score_spread":0.2235615829525173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}