{"id":"W4205495006","doi":"10.1016/j.ygyno.2022.01.014","title":"Contraceptive use and the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation","year":2022,"lang":"en","type":"article","venue":"Gynecologic Oncology","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Juravinski Cancer Centre; Sunnybrook Health Science Centre; BC Cancer Agency; Princess Margaret Cancer Centre; Public Health Ontario; University of Toronto; McMaster University; Women's College Hospital","funders":"","keywords":"BRCA mutation; Ovarian cancer; Odds ratio; Case-control study; Logistic regression; Confidence interval; Breast cancer; Population","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006673917,0.0001300192,0.0002625222,0.00004290615,0.0002770082,0.00001405796,0.0001804266,0.0001193047,0.0006060519],"category_scores_gemma":[0.0004678918,0.00008091789,0.00003411325,0.0001696337,0.0007229368,0.000007330822,0.0002011151,0.0002060247,7.977232e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003517152,"about_ca_system_score_gemma":0.0006544188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004306524,"about_ca_topic_score_gemma":0.003109916,"domain_scores_codex":[0.9983963,0.000683169,0.000227761,0.0003331009,0.0001144116,0.0002452062],"domain_scores_gemma":[0.9987574,0.0004723675,0.0003531009,0.0002427413,0.0001289469,0.00004550273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.05653689,0.001657066,0.5639661,0.0001101227,0.006274004,0.0003327493,0.04427994,0.08658618,0.03535772,0.002730945,0.01541901,0.1867493],"study_design_scores_gemma":[0.01944684,0.0112007,0.8416532,0.000006749929,0.0004330242,0.0002257826,0.01589401,0.0009852406,0.00390866,0.001092197,0.1046263,0.0005272498],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971329,0.0003403395,0.000358244,0.0007222822,0.0002073358,0.0006284753,0.0001294403,0.00001044757,0.0004705178],"genre_scores_gemma":[0.9954894,0.0003211027,0.0008614211,0.0007254278,0.00006154225,0.001732848,0.00002524054,0.00001540717,0.0007675741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2776872,"threshold_uncertainty_score":0.6635844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01238366353848828,"score_gpt":0.2678921849457468,"score_spread":0.2555085214072585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}