{"id":"W4205498339","doi":"10.1002/alz.056250","title":"Development and external validation of a novel dementia risk prediction score in the UK Biobank cohort","year":2021,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Framingham Risk Score; Dementia; Logistic regression; Medicine; Biobank; Cohort; Risk assessment; Physical therapy; Internal medicine; Disease; Computer science; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01197404,0.0006842717,0.0008058843,0.001412832,0.0008902047,0.001740131,0.001174176,0.001259091,0.002596383],"category_scores_gemma":[0.03570195,0.0004276459,0.0005662271,0.001328092,0.0007854503,0.0006023489,0.001849911,0.0009309421,0.001811452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009644373,"about_ca_system_score_gemma":0.001188916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008815775,"about_ca_topic_score_gemma":0.005933426,"domain_scores_codex":[0.9949351,0.002390765,0.0005522139,0.001093916,0.0008198063,0.0002082509],"domain_scores_gemma":[0.9842055,0.00453212,0.002330429,0.004069204,0.004039872,0.0008227509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003873039,0.0008536358,0.9424725,0.0003126615,0.0005414718,0.0006159333,0.00130137,0.001917477,0.003577143,0.000554171,0.01167291,0.03230777],"study_design_scores_gemma":[0.001045967,0.001481133,0.9684738,0.0003265841,0.0003940055,0.001693427,0.0005672102,0.01092912,0.002018932,0.0007064389,0.01227153,0.00009187872],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985128,0.0003347565,0.005832135,0.0001857048,0.00008308759,0.0007182928,0.006549056,0.00007866942,0.001090257],"genre_scores_gemma":[0.9714622,0.0001865562,0.00873552,0.0001871581,0.00006806994,0.001837931,0.01639953,0.00004399303,0.00107902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01197404,"threshold_uncertainty_score":0.06332552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04007119994580084,"score_gpt":0.3021739764433921,"score_spread":0.2621027764975913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}