{"id":"W4205511752","doi":"10.3390/cells11010141","title":"Human and Mouse Eosinophils Differ in Their Ability to Biosynthesize Eicosanoids, Docosanoids, the Endocannabinoid 2-Arachidonoyl-glycerol and Its Congeners","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Impact; University of British Columbia; Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"","keywords":"Arachidonic acid; Lipid signaling; Chemistry; Docosahexaenoic acid; Biochemistry; Leukotriene C4; Endocannabinoid system; Biosynthesis; Leukotriene; Fatty acid; Polyunsaturated fatty acid; Biology; Immunology; Enzyme; Asthma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002913072,0.0002586374,0.0003688792,0.0001288258,0.0003844135,0.00003849818,0.0001760522,0.00005915837,0.0002658766],"category_scores_gemma":[0.00005266421,0.0001727569,0.00007884858,0.0001993225,0.0001826754,0.00005441639,0.0002710404,0.0003124331,0.00001013456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007973044,"about_ca_system_score_gemma":0.00007935952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000358002,"about_ca_topic_score_gemma":0.00001999533,"domain_scores_codex":[0.9983154,0.0002724668,0.0003062107,0.0004966994,0.000239968,0.0003692338],"domain_scores_gemma":[0.9990565,0.0001059592,0.00006761865,0.0004290448,0.00003266735,0.0003082532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003746817,0.0005484826,0.0379636,0.0001782152,0.00004340504,0.00007771933,0.001636562,0.0001028295,0.9498743,0.0001550405,0.003720344,0.005324761],"study_design_scores_gemma":[0.005006257,0.001640949,0.4933093,0.00007007273,0.0001933566,0.00007730127,0.00369604,0.000348661,0.412865,0.000202788,0.08167944,0.0009108886],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936276,0.002409967,0.000001357554,0.002093704,0.0001049205,0.001241105,0.0001549615,0.00004869249,0.0003176561],"genre_scores_gemma":[0.9960935,0.00004983828,0.000008605075,0.002773825,0.0001096655,0.0001990625,0.00001004004,0.00003441877,0.0007210642],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5370094,"threshold_uncertainty_score":0.7044823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01222499847681615,"score_gpt":0.2436431583485663,"score_spread":0.2314181598717502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}