{"id":"W4205514480","doi":"10.1016/j.jval.2021.11.751","title":"POSA236 Real-World Treatment (Tx) Characteristics for Advanced Non-Small Cell Lung Cancer (aNSCLC) Without Actionable Mutations After Introduction of Immune Checkpoint Inhibitors (ICIs) in EU4 and UK","year":2022,"lang":"en","type":"article","venue":"Value in Health","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"GlaxoSmithKline (Canada)","funders":"","keywords":"Pemetrexed; Pembrolizumab; Carboplatin; Lung cancer; Nivolumab; Oncology; Medicine; Internal medicine; Atezolizumab; Cancer; Chemotherapy; Immunotherapy; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004116183,0.000122367,0.0003186062,0.0003060732,0.0001897058,0.0007194857,0.0002595992,0.0003634293,0.007902666],"category_scores_gemma":[0.001830228,0.00007215725,0.0005300695,0.0007240984,0.0001815839,0.0006058929,0.000368355,0.0005941268,0.001017811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009019072,"about_ca_system_score_gemma":0.0005652166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004999415,"about_ca_topic_score_gemma":0.006842566,"domain_scores_codex":[0.9995585,0.00006809885,0.00008437716,0.00009209873,0.00007487689,0.0001220979],"domain_scores_gemma":[0.9988998,0.000217041,0.0004526505,0.00004764327,0.0001352783,0.0002476071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01945151,0.0001274878,0.8681903,0.0004339022,0.0005790102,0.001637302,0.0002225776,0.004248801,0.005891204,0.002161282,0.0159406,0.08111601],"study_design_scores_gemma":[0.0002306038,0.001582413,0.9619665,0.00009748755,0.0001861723,0.001762834,0.0002374497,0.0008647934,0.001181056,0.0006497544,0.03120971,0.00003118107],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.953001,0.003564644,0.000726259,0.001422874,0.0001950175,0.00008079941,0.02475066,0.00006137464,0.01619739],"genre_scores_gemma":[0.9849929,0.0003063996,0.0002012231,0.0003662007,0.00004324965,0.00004488425,0.01087163,0.00003249983,0.003141109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007902666,"threshold_uncertainty_score":0.02643698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01702973960734767,"score_gpt":0.3016004906995064,"score_spread":0.2845707510921587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}