{"id":"W4205524306","doi":"10.1016/s1470-2045(21)00723-3","title":"Radiographic progression-free survival in the ACIS trial for prostate cancer – Authors' reply","year":2021,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Janssen Pharmaceuticals; Astellas Pharma Canada; Bayer; AstraZeneca; Bristol-Myers Squibb","keywords":"Prednisone; Prostate cancer; Abiraterone acetate; Enzalutamide; Placebo; Clinical endpoint; Acis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009076147,0.0007579232,0.002738133,0.0008667528,0.001280128,0.002650828,0.002501209,0.01936419,0.005942337],"category_scores_gemma":[0.0472376,0.000798027,0.001851338,0.00101576,0.002387977,0.003290339,0.001660874,0.03567627,0.002765724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001864122,"about_ca_system_score_gemma":0.003018701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003482246,"about_ca_topic_score_gemma":0.004555723,"domain_scores_codex":[0.995436,0.00198105,0.0007346246,0.0006406733,0.0008028142,0.000404807],"domain_scores_gemma":[0.9685267,0.0242748,0.001546321,0.0008371645,0.003183295,0.001631781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009830487,0.00004445383,0.001043158,0.0002887513,0.0001984106,0.0002434145,0.0001095166,0.0001440289,0.0001086588,0.001247095,0.986499,0.009090601],"study_design_scores_gemma":[0.00454944,0.0005978554,0.009051784,0.001291684,0.0009745808,0.001135475,0.0008514088,0.0008144585,0.001010107,0.01290369,0.9663758,0.0004436417],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0006684648,0.004165513,0.0000710622,0.9436586,0.05046142,0.00001315122,0.0003767651,0.00002275965,0.000562252],"genre_scores_gemma":[0.007271303,0.00273961,0.0001496498,0.8994572,0.08758629,0.0000920305,0.0001951896,0.00003821708,0.002470457],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01936419,"threshold_uncertainty_score":0.04799986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1013740712609857,"score_gpt":0.4442052582376148,"score_spread":0.3428311869766291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}