{"id":"W4205527260","doi":"10.1128/aem.01535-21","title":"Spt20, a Structural Subunit of the SAGA Complex, Regulates Aspergillus fumigatus Biofilm Formation, Asexual Development, and Virulence","year":2021,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Fonds de recherche du Québec; Priority Academic Program Development of Jiangsu Higher Education Institutions; National Natural Science Foundation of China; Government of Canada","keywords":"Conidiation; Biology; Biofilm; Aspergillus fumigatus; Virulence; Protein subunit; Fungal protein; Cell biology; Microbiology; Gene; Saccharomyces cerevisiae; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001224309,0.0005144415,0.000196128,0.0004403342,0.0002384137,0.0003509152,0.0001252905,0.0002116265,0.0007730611],"category_scores_gemma":[0.0001855991,0.0001586678,0.0002209385,0.0001967116,0.0002055058,0.0002156873,0.0002918819,0.000297106,0.0003796313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000372189,"about_ca_system_score_gemma":0.0002033176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001562532,"about_ca_topic_score_gemma":0.001993108,"domain_scores_codex":[0.9998493,0.00002752085,0.00001078096,0.0000239921,0.00005562462,0.00003274553],"domain_scores_gemma":[0.9998746,0.00001070838,0.00003035419,0.000007976191,0.00002744219,0.00004890634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003872249,0.000008156808,0.001011391,0.00001056277,0.000003405777,0.00006050868,0.00001346131,0.0000465867,0.9971831,0.00008006417,0.00006757792,0.001476466],"study_design_scores_gemma":[0.00001952599,0.0002059648,0.09066015,0.00001298235,0.00002464314,0.0008954686,0.0001579101,0.003737826,0.8994748,0.0003488936,0.004447087,0.00001479942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891208,0.003941691,0.003902012,0.0001212881,0.00002658422,0.00001655473,0.0004323842,0.0002155211,0.002223204],"genre_scores_gemma":[0.9970884,0.0006220372,0.0008749421,0.00002947238,0.00000524161,0.000008452792,0.0003591726,0.00002506798,0.0009872571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001562532,"threshold_uncertainty_score":0.003106892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0140615679171465,"score_gpt":0.2068427377939055,"score_spread":0.192781169876759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}