{"id":"W4205545977","doi":"10.1007/s00125-021-05637-7","title":"Metabolic, structural and biochemical changes in diabetes and the development of heart failure","year":2022,"lang":"en","type":"review","venue":"Diabetologia","topic":"Cardiovascular Function and Risk Factors","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates; Killam Trusts; University of Alberta; Heart and Stroke Foundation of Canada","keywords":"Lipotoxicity; Diabetes mellitus; Heart failure; Internal medicine; Medicine; Diabetic cardiomyopathy; Oxidative stress; Endocrinology; Metabolic syndrome; Cardiology; Coronary artery disease; Cardiac function curve; Endothelial dysfunction; Disease; Heart disease; Insulin resistance; Cardiomyopathy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004762167,0.000229935,0.001932795,0.0001722137,0.00005652653,0.000009317828,0.00006774596,0.0001768058,0.0001045163],"category_scores_gemma":[0.0001671695,0.0001205018,0.0002429654,0.0002381347,0.0002481977,0.00001140704,0.0001707075,0.0004003473,0.000001065125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002780837,"about_ca_system_score_gemma":0.0001003725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005348322,"about_ca_topic_score_gemma":0.00001165251,"domain_scores_codex":[0.9988292,0.0001932871,0.0003309999,0.0002722278,0.0001854568,0.0001887781],"domain_scores_gemma":[0.999359,0.0002444624,0.0001074313,0.0002153276,0.00001517617,0.00005860207],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002127058,0.00001953345,0.02695525,0.007459368,0.001096645,0.000003112472,0.0004862049,3.582338e-8,0.00001924439,0.000118204,0.0004450882,0.963376],"study_design_scores_gemma":[0.0007565271,0.00001804869,0.009380382,0.0005506668,0.0007420762,0.0000256849,0.0001247065,0.000001149372,0.000123382,0.00000656644,0.9881294,0.0001413728],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08550933,0.9136457,2.35195e-7,0.0001319274,0.0001198423,0.0005500317,0.00001260591,0.00001467158,0.00001560921],"genre_scores_gemma":[0.003710973,0.9955643,0.0003362481,0.0000634489,0.00004441315,0.0001388072,0.0001059368,0.00001841554,0.00001748297],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9876844,"threshold_uncertainty_score":0.491392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02572490355746795,"score_gpt":0.2811913669218687,"score_spread":0.2554664633644008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}