{"id":"W4205553273","doi":"10.1164/rccm.202106-1485oc","title":"Phase 2B Study of Inhaled RVT-1601 for Chronic Cough in Idiopathic Pulmonary Fibrosis: A Multicenter, Randomized, Placebo-controlled Study (SCENIC Trial)","year":2022,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Placebo; Chronic cough; Clinical endpoint; Idiopathic pulmonary fibrosis; Quality of life (healthcare); Respiratory disease; Inhalation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003708392,0.002029617,0.003041786,0.0005175365,0.0005251099,0.0009547794,0.0009274035,0.002354498,0.004938414],"category_scores_gemma":[0.001589774,0.0008199216,0.001488793,0.0003976289,0.001166727,0.0008195977,0.000363275,0.002389053,0.001048428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004166271,"about_ca_system_score_gemma":0.001575766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004222053,"about_ca_topic_score_gemma":0.0008328179,"domain_scores_codex":[0.9992667,0.0004166806,0.0000464906,0.0001088227,0.00007035654,0.00009094295],"domain_scores_gemma":[0.9991453,0.0001646831,0.0002160109,0.00007088331,0.00009323507,0.0003097713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9480166,0.01692949,0.001287944,0.00115637,0.0006825461,0.00009995476,0.00006715388,0.0003612569,0.01328934,0.0001843149,0.001531867,0.01639295],"study_design_scores_gemma":[0.9414706,0.05630992,0.001033319,0.00002183562,0.0001488909,0.00003004277,0.000008983191,0.0001409266,0.0003995082,0.00004858737,0.0003802997,0.000007036867],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9680839,0.008945417,0.001455864,0.001483955,0.0009089125,0.01466652,0.002130765,0.0002282907,0.002096326],"genre_scores_gemma":[0.9519154,0.005817249,0.005303302,0.003431889,0.001612032,0.02453806,0.002921419,0.00005455614,0.004406078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004938414,"threshold_uncertainty_score":0.01961207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01820275379254836,"score_gpt":0.341508075975043,"score_spread":0.3233053221824946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}