{"id":"W4205574712","doi":"10.1016/j.freeradbiomed.2021.08.069","title":"Receptor for advanced glycation end products and glyoxalase-1 in the total circulating extracellular vesicles from mild cognitive impairment and Alzheimer’s disease patients","year":2021,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke; Institut National de la Recherche Scientifique","funders":"","keywords":"Chemistry; Arachidonic acid; Chromatography; Glycation; Cyclooxygenase; Thromboxane B2; Extraction (chemistry); Epoxyeicosatrienoic acid; Receptor; Internal medicine; Biochemistry; Pharmacology; Endocrinology; Enzyme; Biology; Medicine; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001553333,0.0002791676,0.0004853767,0.0004910062,0.0003867556,0.0006289359,0.0002566998,0.0003613904,0.002408309],"category_scores_gemma":[0.0006836894,0.000191032,0.0002450261,0.0002434742,0.0001469121,0.0003274775,0.0003488398,0.0005486466,0.0002885261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002090865,"about_ca_system_score_gemma":0.0001453493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002448133,"about_ca_topic_score_gemma":0.001387423,"domain_scores_codex":[0.9998728,0.00001688077,0.00001353008,0.00002970071,0.00002429635,0.0000427322],"domain_scores_gemma":[0.9998655,0.00002207176,0.00003589543,0.00001016787,0.00002917382,0.00003718496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0230625,0.0008531001,0.7280787,0.0003742875,0.000761729,0.005074209,0.002463193,0.0002304285,0.1952719,0.0005294862,0.00208793,0.04121247],"study_design_scores_gemma":[0.0001483722,0.0007341853,0.9841925,0.00002927952,0.0002801014,0.003462507,0.001150008,0.0007747749,0.0076214,0.0002384181,0.001344883,0.00002357871],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998984,0.0005245245,0.00005458143,0.00003198326,0.00001646764,0.000004415683,0.0001384739,0.000002836392,0.0002426833],"genre_scores_gemma":[0.998645,0.000176926,0.0000517388,0.00003882759,0.00001828603,0.000007702,0.0002565697,0.000002206837,0.0008026698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002448133,"threshold_uncertainty_score":0.008056581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01717871565334911,"score_gpt":0.2784908095421699,"score_spread":0.2613120938888208,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}