{"id":"W4205615658","doi":"10.1186/s10194-021-01377-6","title":"Assessment of peripheral biomarkers potentially involved in episodic and chronic migraine: a case-control study with a focus on NGF, BDNF, VEGF, and PGE2","year":2022,"lang":"en","type":"article","venue":"The Journal of Headache and Pain","topic":"Migraine and Headache Studies","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute","funders":"National Institute for Medical Research Development","keywords":"Medicine; Migraine; Nerve growth factor; Internal medicine; Neurology; Pathophysiology; Vascular endothelial growth factor; Neurotrophin; Peripheral; Neurotrophic factors; Chronic Migraine; Endocrinology; Case-control study; Gastroenterology; Receptor; VEGF receptors; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001042948,0.0004533223,0.0006946626,0.0009458218,0.0007766574,0.0005713867,0.0003721332,0.0006822854,0.001136794],"category_scores_gemma":[0.001680787,0.0004844028,0.0003886316,0.001049303,0.0004320236,0.0003533739,0.0003866649,0.0004022058,0.0001478003],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002626722,"about_ca_system_score_gemma":0.0002243776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002524676,"about_ca_topic_score_gemma":0.002636719,"domain_scores_codex":[0.9990917,0.0002224183,0.0001232342,0.0003263783,0.0001427991,0.00009340396],"domain_scores_gemma":[0.9990916,0.0001939549,0.0003395869,0.0001268368,0.0001204151,0.000127573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004980087,0.0001921786,0.9960707,0.00003449692,0.000124241,0.0005859507,0.0001930228,0.00001325147,0.0009133404,0.0000335931,0.00005844038,0.001282738],"study_design_scores_gemma":[0.00004140997,0.0004668807,0.9973938,0.000007913043,0.00009993416,0.001532572,0.0001266232,0.00007184956,0.00007160353,0.0000209943,0.0001626834,0.000003653282],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989525,0.0005736473,0.0001729215,0.00001311607,0.000005851793,0.00002774969,0.00006537914,0.000001719738,0.000187039],"genre_scores_gemma":[0.9993691,0.0001722327,0.000168267,0.00002026557,0.0000153923,0.00002665338,0.0001150385,0.00000105299,0.0001120708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002524676,"threshold_uncertainty_score":0.005515695,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01405767377034386,"score_gpt":0.2788576409527793,"score_spread":0.2647999671824355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}