{"id":"W4205632133","doi":"10.51731/cjht.2021.187","title":"Brexucabtagene Autoleucel (Tecartus)","year":2021,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Reimbursement; Mantle cell lymphoma; Chimeric antigen receptor; Bruton's tyrosine kinase; Medicine; CD19; Lymphoma; Drug; Immunotherapy; Cell therapy; Oncology; Tyrosine kinase; Pharmacology; Immunology; Internal medicine; Cell; Antigen; Receptor; Cancer; Biology; Health care; Political science","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009652477,0.0001727798,0.0003825996,0.001004557,0.0001924241,0.0007809853,0.0003066697,0.000377019,0.003807687],"category_scores_gemma":[0.0009814225,0.00005726645,0.0004288433,0.000821923,0.0002412213,0.0002754209,0.0001609474,0.0005298372,0.0005629993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0022415,"about_ca_system_score_gemma":0.00198458,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01480047,"about_ca_topic_score_gemma":0.05479344,"domain_scores_codex":[0.9994519,0.0001283253,0.00003532262,0.00003705502,0.0003046567,0.00004274135],"domain_scores_gemma":[0.9995004,0.0001768055,0.0001208377,0.00001435607,0.0001454051,0.00004224549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005537862,0.00008313233,0.001228419,0.005618467,0.0002359599,0.0002192814,0.00004824126,0.0004623526,0.008193943,0.003821617,0.02686048,0.9526744],"study_design_scores_gemma":[0.000242488,0.001019162,0.007440902,0.002721509,0.0003256709,0.001488495,0.00007103351,0.0002388661,0.008046385,0.0003637143,0.9780225,0.00001936891],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.01512149,0.956212,0.001034016,0.001695802,0.0002430667,0.0001356416,0.0009223141,0.00007161627,0.02456404],"genre_scores_gemma":[0.1917224,0.7768171,0.00388422,0.002293879,0.0002452254,0.0001956258,0.002190762,0.00003934743,0.02261132],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9851995,"threshold_uncertainty_score":0.0294286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05133370576819875,"score_gpt":0.3399551668119211,"score_spread":0.2886214610437224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}