{"id":"W4205694558","doi":"10.21203/rs.3.rs-1019411/v1","title":"Serotonin regulation of behaviour via large-scale neuromodulation of serotonin receptor networks","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Neural dynamics and brain function","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"Wellcome Trust","keywords":"Neuromodulation; Serotonin; 5-HT receptor; Neuroscience; Serotonergic; Psychology; Receptor; Biology; Medicine; Internal medicine; Stimulation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001972953,0.000273006,0.0004611803,0.0005735167,0.000345448,0.00006401765,0.0006580165,0.0003388176,0.001112766],"category_scores_gemma":[0.0004598041,0.0002870635,0.0002541076,0.001112102,0.0001823165,0.0001662272,0.001632562,0.001852206,0.000009596925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002433606,"about_ca_system_score_gemma":0.0001617783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001988638,"about_ca_topic_score_gemma":0.00003956115,"domain_scores_codex":[0.9942739,0.001479604,0.0007277788,0.001001292,0.001921624,0.0005958034],"domain_scores_gemma":[0.9973421,0.0004859405,0.0005459268,0.001021209,0.0004748316,0.0001300085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0008004652,0.0009986188,0.03274573,0.00139117,0.00001922571,0.00001547385,0.0006493273,0.2540568,0.7015442,0.002296796,0.001118889,0.004363291],"study_design_scores_gemma":[0.0007080929,0.001183062,0.1562909,0.0004220441,0.00002423011,0.000007643481,0.0001706901,0.7130761,0.1240129,0.002416578,0.001238807,0.0004490281],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911671,0.00004974785,0.003702513,0.0003263048,0.0008728985,0.002927972,0.0004256086,0.00008014705,0.0004476842],"genre_scores_gemma":[0.9975435,0.0001376104,0.0002690216,0.00002449204,0.0001426494,0.0004121875,0.0005055831,0.00007152916,0.0008934274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5775313,"threshold_uncertainty_score":0.9999582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05672473482629166,"score_gpt":0.3531140135295803,"score_spread":0.2963892787032886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}