{"id":"W4205716810","doi":"10.1093/mr/roab030","title":"Efficacy and safety of filgotinib in combination with methotrexate in Japanese patients with active rheumatoid arthritis who have an inadequate response to methotrexate: Subpopulation analyses of 24-week data of a global phase 3 study (FINCH 1)","year":2021,"lang":"en","type":"article","venue":"Modern Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"Gilead Sciences","keywords":"Medicine; Adalimumab; Rheumatoid arthritis; Internal medicine; Methotrexate; Placebo; Rheumatology; Incidence (geometry); Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002487613,0.0005824513,0.001834812,0.0003756606,0.000342994,0.0005302696,0.0003276315,0.0005394621,0.0005252623],"category_scores_gemma":[0.001314698,0.0003013958,0.001502292,0.0004103942,0.0003456183,0.0003947797,0.000301836,0.0006539972,0.0001270182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00040517,"about_ca_system_score_gemma":0.0004815003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009370614,"about_ca_topic_score_gemma":0.002039343,"domain_scores_codex":[0.999258,0.0003537946,0.00007733081,0.0001177196,0.0001117669,0.00008146065],"domain_scores_gemma":[0.9988525,0.0002312729,0.0004324164,0.0001437623,0.0001055496,0.0002345485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2492094,0.003463205,0.625257,0.0007103365,0.008566048,0.0007408137,0.0008814748,0.00148577,0.03997944,0.00005408706,0.001089873,0.06856263],"study_design_scores_gemma":[0.02362031,0.06282245,0.9029506,0.00004278859,0.004514782,0.00106336,0.0002452948,0.001406397,0.001956811,0.00007237677,0.001235994,0.00006880549],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998871,0.0008427632,0.00004634512,0.00001836326,0.000002965891,0.00002962229,0.0000846862,0.000003592498,0.0001006053],"genre_scores_gemma":[0.9990838,0.0002300079,0.0001191298,0.00006043133,0.0000188869,0.00003555215,0.0003766516,0.000003004627,0.00007251518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002487613,"threshold_uncertainty_score":0.01315594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05647267915729292,"score_gpt":0.3770424868313791,"score_spread":0.3205698076740862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}