{"id":"W4205745128","doi":"10.1021/acs.est.1c07268","title":"Urinary Eicosanoid Levels Reflect Allergen and Diesel Exhaust Coexposure and Are Linked to Impaired Lung Function","year":2022,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"Air Quality and Health Impacts","field":"Environmental Science","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Ontario; University of Toronto; University of British Columbia","funders":"Canadian Institutes of Health Research; Vetenskapsrådet; Natural Sciences and Engineering Research Council of Canada; AllerGen; Michael Smith Health Research BC","keywords":"Eicosanoid; Leukotriene; Inhalation; Leukotriene E4; Prostaglandin D2; Immunology; Allergen; Urinary system; Medicine; Prostaglandin; Asthma; Pharmacology; Chemistry; Internal medicine; Allergy; Anesthesia; Arachidonic acid; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009046653,0.0004763508,0.0006855348,0.000507965,0.0002836036,0.0004523398,0.0002451359,0.0008008048,0.001316274],"category_scores_gemma":[0.00131338,0.000305579,0.0003315997,0.0004504566,0.0003728248,0.0002457867,0.0004395678,0.0005441816,0.0001580052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001732195,"about_ca_system_score_gemma":0.0001664162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003835784,"about_ca_topic_score_gemma":0.000552947,"domain_scores_codex":[0.9992639,0.0002061355,0.00006376341,0.0001892367,0.000188854,0.00008815949],"domain_scores_gemma":[0.9990772,0.0001733734,0.0003438506,0.0001427069,0.00008158849,0.0001812661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02796971,0.003546704,0.6362689,0.0002141495,0.0005492517,0.000272417,0.0002776011,0.0003356866,0.3173875,0.0000787606,0.0001207679,0.0129786],"study_design_scores_gemma":[0.00007641267,0.008039896,0.9740438,0.000004652351,0.0001439145,0.0002888957,0.00007421902,0.0002548333,0.0167795,0.00004818919,0.0002372152,0.000008455607],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989727,0.0003111685,0.0003680116,0.00000987473,0.000004893691,0.00006325841,0.0001207547,0.000006606909,0.0001428193],"genre_scores_gemma":[0.9986954,0.0001139493,0.0004827392,0.00002648011,0.00000558051,0.00006603711,0.0001935493,0.000003383388,0.0004127763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001316274,"threshold_uncertainty_score":0.004784405,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02563535329998433,"score_gpt":0.2783612585954551,"score_spread":0.2527259052954707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}