{"id":"W4205781711","doi":"10.1002/hep.32314","title":"Getting to HBV cure: The promising paths forward","year":2022,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Liver Centre; Toronto General Hospital","funders":"","keywords":"cccDNA; Hepatitis B virus; Immune system; Hepatitis B; Innate immune system; Antigen; Lamivudine; Chronic hepatitis; Viral replication","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003814809,0.0001183747,0.0003068897,0.00007742024,0.0005795679,0.000007885216,0.0001390637,0.00003654515,0.0003713865],"category_scores_gemma":[0.0003924928,0.00008878663,0.00007424327,0.0002556226,0.00006527937,0.0000203499,0.0004059697,0.0003358621,0.0001326358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001471154,"about_ca_system_score_gemma":0.0001142482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005252843,"about_ca_topic_score_gemma":0.0004806093,"domain_scores_codex":[0.9987041,0.000165351,0.0002393455,0.0002632352,0.0002378201,0.0003901727],"domain_scores_gemma":[0.9993238,0.0001566507,0.00006178028,0.0003205282,0.0000558865,0.00008134605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001013576,0.00008486961,0.9128689,0.00004444477,0.0001009079,0.0003856243,0.004696142,0.000008095045,0.002222413,0.002174266,0.06206228,0.01525072],"study_design_scores_gemma":[0.0007929619,0.0006166619,0.03951904,0.00002542566,0.0001137339,0.0009039736,0.0007769404,0.001354907,0.001013112,0.000811805,0.9538344,0.000237076],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9507977,0.0006658661,0.0002256295,0.04071402,0.0005687342,0.0006892142,0.00001279952,0.0001176016,0.006208381],"genre_scores_gemma":[0.9865272,0.00002942003,0.000789599,0.01149494,0.0001465769,0.0003098029,0.000006390822,0.00002600001,0.0006700526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8917721,"threshold_uncertainty_score":0.4457626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02607236027219235,"score_gpt":0.2965860896408639,"score_spread":0.2705137293686716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}