{"id":"W4205781711","doi":"10.1002/hep.32314","title":"Getting to HBV cure: The promising paths forward","year":2022,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Liver Centre; Toronto General Hospital","funders":"","keywords":"cccDNA; Hepatitis B virus; Immune system; Hepatitis B; Innate immune system; Antigen; Lamivudine; Chronic hepatitis; Viral replication","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003130745,0.000718911,0.001256386,0.0009811542,0.0008876272,0.003085202,0.000762828,0.002931153,0.01309635],"category_scores_gemma":[0.003566033,0.000274322,0.0007937711,0.0007118694,0.001429649,0.005079772,0.002113217,0.0067829,0.004813803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001018278,"about_ca_system_score_gemma":0.003473535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007998305,"about_ca_topic_score_gemma":0.001848797,"domain_scores_codex":[0.9989875,0.0003483107,0.00009207755,0.000116108,0.0002621462,0.0001939478],"domain_scores_gemma":[0.9970453,0.001548666,0.0001564392,0.0001055551,0.0006104462,0.0005335796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003445422,0.0002181913,0.0005397007,0.009760306,0.0001049771,0.0004209405,0.0004415539,0.0003223537,0.002330071,0.02763639,0.2089105,0.7489706],"study_design_scores_gemma":[0.00004519373,0.0003278982,0.000548789,0.003433183,0.00006416866,0.0005585224,0.0005376723,0.0001609341,0.0005252632,0.01448746,0.9792778,0.00003314362],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006251514,0.9385715,0.001035651,0.04928353,0.005477035,0.00002232355,0.0001062415,0.0001076147,0.00477091],"genre_scores_gemma":[0.006636228,0.9641784,0.00268274,0.01735901,0.004687316,0.00005465961,0.0002093747,0.00004361453,0.004148623],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01309635,"threshold_uncertainty_score":0.04381168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02607236027219235,"score_gpt":0.2965860896408639,"score_spread":0.2705137293686716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}