{"id":"W4205817019","doi":"10.2139/ssrn.3982675","title":"P66Shc is an Apoptotic Rheostat Whose Targeted ROS Inhibition Improves Myocardial Infarction Outcomes","year":2021,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Blood properties and coagulation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Lethbridge","funders":"","keywords":"Myocardial infarction; Apoptosis; Internal medicine; Cancer research; Medicine; Cell biology; Cardiology; Chemistry; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001865138,0.000241285,0.0003034388,0.0002151344,0.0001500636,0.0004601844,0.0001649767,0.0003286052,0.004420953],"category_scores_gemma":[0.0003400199,0.00009868524,0.0002295478,0.0001705532,0.0001923005,0.0002059186,0.0002583156,0.0009395964,0.0008273823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001960656,"about_ca_system_score_gemma":0.0002786307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002419865,"about_ca_topic_score_gemma":0.0003708744,"domain_scores_codex":[0.9999181,0.00001614618,0.000009419998,0.00001275919,0.0000220681,0.00002147799],"domain_scores_gemma":[0.9999205,0.000008149092,0.00003348358,0.000008376518,0.00001190391,0.00001762191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02169995,0.001609201,0.01174497,0.001399136,0.0006685769,0.001021646,0.000114281,0.0009884408,0.5651547,0.003575824,0.01692702,0.3750963],"study_design_scores_gemma":[0.01386361,0.02073182,0.1033861,0.0006010809,0.002100229,0.006843444,0.0005452929,0.007418884,0.7071258,0.00825921,0.1289927,0.0001317625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9363118,0.04108176,0.003442503,0.004233164,0.001097961,0.0001492624,0.0009760491,0.0004087781,0.01229878],"genre_scores_gemma":[0.986711,0.007063257,0.0009538476,0.0005149675,0.000240865,0.00003791906,0.0005212521,0.00002058521,0.003936271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004420953,"threshold_uncertainty_score":0.01478958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0109418217026325,"score_gpt":0.2478273729801182,"score_spread":0.2368855512774857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}