{"id":"W4205818897","doi":"10.21203/rs.3.rs-48885/v2","title":"Partnering with Patients to Get Better Outcomes with Chimeric Antigen Receptor T-cell Therapy: Towards Engagement of Patients in Early Phase Trials&amp;nbsp;&amp;nbsp;","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Mental Health and Patient Involvement","field":"Health Professions","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Ottawa Hospital","funders":"Government of Canada","keywords":"Chimeric antigen receptor; Medicine; Receptor; Internal medicine; T cell; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01453907,0.0002721922,0.0003169272,0.0002347539,0.001396156,0.003828237,0.0005539023,0.002096648,0.02307127],"category_scores_gemma":[0.02691819,0.0001714105,0.0004487487,0.0003328917,0.001026339,0.002094004,0.003846229,0.003540394,0.005536388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009195261,"about_ca_system_score_gemma":0.005396266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006741629,"about_ca_topic_score_gemma":0.001990449,"domain_scores_codex":[0.9911399,0.006481833,0.0001337627,0.0003914893,0.0009443259,0.0009087364],"domain_scores_gemma":[0.9851298,0.005216243,0.001358284,0.0006765904,0.0009041653,0.006714946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002206073,0.002279241,0.02152719,0.0005352534,0.0001565244,0.000306066,0.00284813,0.0007673259,0.003442693,0.01373518,0.2197444,0.7324519],"study_design_scores_gemma":[0.005277296,0.006149207,0.06853459,0.002618617,0.0004008333,0.001458403,0.009362918,0.006166616,0.01256397,0.1521392,0.7351319,0.0001964976],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.2028305,0.008691689,0.03380961,0.5295222,0.004693118,0.001455053,0.001162273,0.0007348784,0.2171007],"genre_scores_gemma":[0.816621,0.006073915,0.04026109,0.08870609,0.002671101,0.002345809,0.001201195,0.0002929465,0.04182684],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02307127,"threshold_uncertainty_score":0.07718104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5494197582429998,"score_gpt":0.5575196662812777,"score_spread":0.00809990803827787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}