{"id":"W4205886054","doi":"10.1016/j.nmd.2021.07.165","title":"DMD - TREATMENT","year":2021,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Dystrophin; Duchenne muscular dystrophy; Exon skipping; Medicine; Interim analysis; Clinical trial; Physical medicine and rehabilitation; Internal medicine; Physical therapy; Exon; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003083033,0.0001701161,0.0001291463,0.0000219899,0.0001047441,0.00001442441,0.0001102856,0.0001093501,0.0001497272],"category_scores_gemma":[0.00005795752,0.0001654519,0.0002119423,0.00009972639,0.00007492675,0.000002838451,0.00006617885,0.00005473401,0.0000518936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006610576,"about_ca_system_score_gemma":0.00009230059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001887397,"about_ca_topic_score_gemma":0.0001827438,"domain_scores_codex":[0.9989867,0.000102941,0.0001187013,0.0004557066,0.00008357656,0.0002523386],"domain_scores_gemma":[0.9993535,0.000008646138,0.00002994552,0.0004971585,0.00003387858,0.00007689706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001729928,0.0008429262,0.01006922,0.00002754823,0.0002739154,0.0000343351,0.00009297045,0.0006302651,0.9325326,0.0008014495,0.00449365,0.05002815],"study_design_scores_gemma":[0.002520728,0.001116297,0.03876083,0.00000572515,0.0000701617,0.00002537672,0.0002245013,0.00005184559,0.1158765,0.001382449,0.8394117,0.0005538677],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858481,0.00192384,0.0004428175,0.0006510996,0.0002571727,0.0001249093,0.000008316085,0.00002947808,0.01071431],"genre_scores_gemma":[0.995387,0.001828371,0.000137559,0.001003139,0.00009379327,0.00003644919,0.0002618041,0.00002884059,0.001223015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8349181,"threshold_uncertainty_score":0.6746931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00648083803485932,"score_gpt":0.2311448718326305,"score_spread":0.2246640337977712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}