{"id":"W4205890796","doi":"10.2147/copd.s329783","title":"SARS-CoV-2 (COVID-19) Adhesion Site Protein Upregulation in Small Airways, Type 2 Pneumocytes, and Alveolar Macrophages of Smokers and COPD – Possible Implications for Interstitial Fibrosis","year":2022,"lang":"en","type":"article","venue":"International Journal of COPD","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Rebecca L. Cooper Medical Research Foundation; Clifford Craig Foundation","keywords":"Interstitial lung disease; Downregulation and upregulation; COPD; Fibrosis; Idiopathic pulmonary fibrosis; Pulmonary fibrosis; Lung; Lung function","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003166346,0.0001238373,0.0002654292,0.0003448378,0.0000960229,0.00003330616,0.0001594402,0.00005264156,0.00004559705],"category_scores_gemma":[0.0002158331,0.0001216968,0.0001276609,0.0001346197,0.00008928558,0.000169415,0.0001221418,0.000176038,4.845219e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002862999,"about_ca_system_score_gemma":0.0003039896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002267751,"about_ca_topic_score_gemma":0.00003316142,"domain_scores_codex":[0.9988409,0.0000675117,0.0005254076,0.0001814042,0.0002542213,0.0001305012],"domain_scores_gemma":[0.9989135,0.0001034282,0.0003782855,0.0001006555,0.0003931428,0.0001109741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01841941,0.0004010809,0.02229054,0.0003464325,0.0002037188,0.00007983011,0.0006839059,0.0002035143,0.947077,0.002226015,0.002232031,0.005836521],"study_design_scores_gemma":[0.03985872,0.06221043,0.4442731,0.00586464,0.001705634,0.006057815,0.003069359,0.01893423,0.2863188,0.02559998,0.1041313,0.001976082],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914307,0.001998466,0.001188299,0.004273747,0.0002739794,0.0004469963,0.0003068739,0.000009460065,0.00007150063],"genre_scores_gemma":[0.997668,0.0001553004,0.001312435,0.0004949644,0.0001505998,0.00002897745,0.00008264297,0.00001761748,0.00008941894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6607583,"threshold_uncertainty_score":0.496265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03521336933018947,"score_gpt":0.3274866537861636,"score_spread":0.2922732844559741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}