{"id":"W4205890796","doi":"10.2147/copd.s329783","title":"SARS-CoV-2 (COVID-19) Adhesion Site Protein Upregulation in Small Airways, Type 2 Pneumocytes, and Alveolar Macrophages of Smokers and COPD – Possible Implications for Interstitial Fibrosis","year":2022,"lang":"en","type":"article","venue":"International Journal of COPD","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Rebecca L. Cooper Medical Research Foundation; Clifford Craig Foundation","keywords":"Interstitial lung disease; Downregulation and upregulation; COPD; Fibrosis; Idiopathic pulmonary fibrosis; Pulmonary fibrosis; Lung; Lung function","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002260998,0.0001670413,0.0002132579,0.0003542048,0.0001803888,0.0002194923,0.00008139465,0.0002664743,0.001445193],"category_scores_gemma":[0.0002066293,0.0001620137,0.0001803481,0.0001637294,0.0002027968,0.0001524699,0.0002135548,0.0001861354,0.0002181008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007614247,"about_ca_system_score_gemma":0.0000829964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000332294,"about_ca_topic_score_gemma":0.0005026478,"domain_scores_codex":[0.9998647,0.00003052132,0.00001464906,0.00003744871,0.00002838753,0.00002427456],"domain_scores_gemma":[0.9998742,0.00001803699,0.00003302843,0.00001088965,0.00002075811,0.00004308689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001570772,0.0001454925,0.6048649,0.0000773819,0.00006774358,0.0008444964,0.0003275595,0.00002426642,0.3889762,0.00003175641,0.00009100824,0.002978406],"study_design_scores_gemma":[0.000009293963,0.0002430691,0.993642,0.000003099966,0.00001856937,0.001170238,0.0001607062,0.00006567728,0.004534211,0.00001327329,0.0001382608,0.000001585072],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995968,0.0001699797,0.00005303029,0.000006733279,0.00000207615,0.000003634584,0.00003978366,0.000001267958,0.0001268065],"genre_scores_gemma":[0.9995204,0.00007852869,0.0000782594,0.00001428436,0.000006991027,0.000008978574,0.0001137806,8.262789e-7,0.000177887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001445193,"threshold_uncertainty_score":0.004834712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03521336933018947,"score_gpt":0.3274866537861636,"score_spread":0.2922732844559741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}