{"id":"W4205918029","doi":"10.1182/blood.2021014027","title":"Sirolimus plus prednisolone vs sirolimus monotherapy for kaposiform hemangioendothelioma: a randomized clinical trial","year":2022,"lang":"en","type":"article","venue":"Blood","topic":"Vascular Malformations and Hemangiomas","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"West China Hospital, Sichuan University; Sichuan University; National Natural Science Foundation of China","keywords":"Medicine; Sirolimus; Prednisolone; Surgery; Combination therapy; Adverse effect; Internal medicine; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002226644,0.001667797,0.003688051,0.0005225527,0.0004639863,0.001351531,0.001034969,0.002407709,0.006636626],"category_scores_gemma":[0.002159761,0.0006470233,0.002214332,0.0005022249,0.001118271,0.001232891,0.0004606597,0.003295304,0.0009429376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006465095,"about_ca_system_score_gemma":0.001082595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006042275,"about_ca_topic_score_gemma":0.001156137,"domain_scores_codex":[0.9990114,0.0005794289,0.00007721925,0.0001412671,0.00007122242,0.000119511],"domain_scores_gemma":[0.998642,0.0004862605,0.0003305217,0.00008893122,0.00008758045,0.0003646465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9880884,0.003866609,0.0002240037,0.0004362713,0.0007923329,0.00002846345,0.00002137881,0.0001498544,0.0008241819,0.00006271245,0.0002500959,0.005255645],"study_design_scores_gemma":[0.9532331,0.04470808,0.0006122766,0.00003457188,0.0005724925,0.00001920616,0.00001598497,0.0002642862,0.0001494108,0.00009685323,0.000285397,0.000008364553],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981231,0.008860968,0.0005140316,0.001075338,0.001244267,0.004294461,0.0007028378,0.0001047031,0.001972415],"genre_scores_gemma":[0.9847311,0.004187907,0.001043968,0.001214134,0.0009475788,0.005242493,0.0005808785,0.00001468481,0.002037236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006636626,"threshold_uncertainty_score":0.02220172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04166809924571527,"score_gpt":0.3345935149485713,"score_spread":0.292925415702856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}