{"id":"W4205922358","doi":"10.1016/j.cjca.2022.01.012","title":"Critical Role of Extracellular Matrix Remodelling in Patients With Dilated Cardiomyopathy: Lessons From Connective Tissue Disorders","year":2022,"lang":"en","type":"letter","venue":"Canadian Journal of Cardiology","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Extracellular matrix; Connective tissue; Matricellular protein; Marfan syndrome; Dilated cardiomyopathy; Cardiomyopathy; Matrix metalloproteinase; Heart failure; Internal medicine; Pathology; Cardiology; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001706801,0.0006321902,0.001908393,0.0006214891,0.001194116,0.001998917,0.001021067,0.01595649,0.002457423],"category_scores_gemma":[0.01129573,0.0003526596,0.0008941439,0.0005401498,0.002267516,0.002607411,0.0007381985,0.01281151,0.0009295713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00200759,"about_ca_system_score_gemma":0.001301334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002203076,"about_ca_topic_score_gemma":0.003037764,"domain_scores_codex":[0.9988958,0.0003574277,0.0001730505,0.0001618676,0.0002321395,0.0001798271],"domain_scores_gemma":[0.9928125,0.005163311,0.000292483,0.0002146772,0.0007849509,0.0007321548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00126692,0.0002558635,0.02762979,0.0007027411,0.0002612452,0.2063559,0.001510484,0.000467908,0.00312653,0.02139972,0.6384619,0.09856094],"study_design_scores_gemma":[0.002681842,0.0005782238,0.05339161,0.003257372,0.0006218432,0.2719299,0.002724171,0.003362241,0.001448105,0.09547141,0.5641783,0.0003548429],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.009730857,0.02821896,0.0004680293,0.939236,0.01626014,0.0000168325,0.00007927788,0.0000346908,0.00595518],"genre_scores_gemma":[0.1466061,0.02919727,0.0009941232,0.3832577,0.4360261,0.00005541544,0.00008093475,0.00004940911,0.003733017],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.01595649,"threshold_uncertainty_score":0.01456612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009242154562740804,"score_gpt":0.2605441139123375,"score_spread":0.2513019593495967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}