{"id":"W4205929832","doi":"10.1093/abt/tbab030","title":"CellCelector™ as a platform in isolating primary B cells for antibody discovery","year":2022,"lang":"en","type":"article","venue":"Antibody Therapeutics","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Amgen (Canada)","funders":"Amgen","keywords":"Antibody; Antibody Repertoire; Biology; Recombinant DNA; B cell; Antigen; Immune system; Complementarity determining region; Computational biology; Immunoglobulin light chain; Immunology; Molecular biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007856678,0.0006366701,0.0003779075,0.0006604541,0.0003638172,0.0006433057,0.0005912199,0.0005245914,0.003477153],"category_scores_gemma":[0.0003365834,0.0004607686,0.0004019199,0.000336585,0.0002968795,0.0003420261,0.0006379371,0.001128426,0.004680354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002137498,"about_ca_system_score_gemma":0.0004048368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003281804,"about_ca_topic_score_gemma":0.0007330319,"domain_scores_codex":[0.9994463,0.0001102368,0.00003051163,0.0001126029,0.0002431902,0.00005717975],"domain_scores_gemma":[0.9997674,0.00007219853,0.00003858304,0.00003982541,0.00004418293,0.00003774585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004570978,0.00002927659,0.0001841217,0.00007905297,0.000008081925,0.00005561185,0.00002954754,0.00011484,0.9898648,0.0005549604,0.0005042824,0.008529916],"study_design_scores_gemma":[0.00004033242,0.000368656,0.001403338,0.00002975963,0.00003590179,0.0008244578,0.00002262351,0.002055079,0.9465569,0.0004267916,0.04821823,0.0000179883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2096608,0.006645439,0.758936,0.0007738739,0.000331274,0.001504709,0.00245912,0.003193769,0.01649508],"genre_scores_gemma":[0.2732934,0.005561305,0.6909573,0.0006868985,0.0001536489,0.001818198,0.005303503,0.0004935499,0.02173222],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003477153,"threshold_uncertainty_score":0.01163226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04107785918090384,"score_gpt":0.3649219867184469,"score_spread":0.3238441275375431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}