{"id":"W4205936314","doi":"10.1089/thy.2021.0535","title":"Congenital Hypothyroidism and Hyperthyroidism Alters Adrenal Gene Expression, Development, and Function","year":2022,"lang":"en","type":"article","venue":"Thyroid","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Novo Nordisk Fonden","keywords":"Endocrinology; Adrenarche; Internal medicine; Adrenal cortex; Medicine; Hormone; Thyroid; Adrenal gland; Adrenal medulla; Catecholamine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001408719,0.0002673626,0.0003053282,0.0001571342,0.0006277994,0.00003346801,0.00006872079,0.00005799677,0.0001423227],"category_scores_gemma":[0.0000206597,0.0002408889,0.00005502172,0.0001491424,0.0001036162,0.0001297828,0.0002453839,0.000236022,0.00002125066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007802456,"about_ca_system_score_gemma":0.0001027066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003152613,"about_ca_topic_score_gemma":0.000007042854,"domain_scores_codex":[0.9984578,0.00006109088,0.0002793291,0.0004961586,0.0003554637,0.0003501141],"domain_scores_gemma":[0.9993164,0.00004121083,0.00008951101,0.0002431328,0.00003526512,0.0002744796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003451658,0.001440174,0.09243253,0.00006548713,0.0008165711,0.0005792275,0.004939509,0.00001200417,0.8299853,0.0004235352,0.02204621,0.04380779],"study_design_scores_gemma":[0.04789467,0.006575837,0.6089985,0.00005773857,0.001245685,0.005287742,0.00819935,0.0003795411,0.1812564,0.00221452,0.1355611,0.002328965],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9803258,0.01703967,0.0001601205,0.0003130435,0.0001691518,0.0004087101,0.00003233111,0.0001094883,0.001441662],"genre_scores_gemma":[0.9948139,0.0002022395,0.002027783,0.0006669712,0.00007582486,0.0001420821,0.0001653642,0.0000464272,0.001859404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.648729,"threshold_uncertainty_score":0.9823164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01351742380406601,"score_gpt":0.2184450936355031,"score_spread":0.2049276698314371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}