{"id":"W4205936314","doi":"10.1089/thy.2021.0535","title":"Congenital Hypothyroidism and Hyperthyroidism Alters Adrenal Gene Expression, Development, and Function","year":2022,"lang":"en","type":"article","venue":"Thyroid","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Novo Nordisk Fonden","keywords":"Endocrinology; Adrenarche; Internal medicine; Adrenal cortex; Medicine; Hormone; Thyroid; Adrenal gland; Adrenal medulla; Catecholamine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001614175,0.0001994621,0.0001328562,0.0003892865,0.00009274602,0.0002309777,0.0001598845,0.0001810571,0.001044558],"category_scores_gemma":[0.000261891,0.0000875732,0.0001849148,0.0001776968,0.0003538951,0.000110283,0.0001817446,0.0002335993,0.00009384062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003395579,"about_ca_system_score_gemma":0.0003025061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009818134,"about_ca_topic_score_gemma":0.001261565,"domain_scores_codex":[0.9997925,0.00002916807,0.00001347802,0.00005702069,0.00007251031,0.00003534861],"domain_scores_gemma":[0.9997652,0.00005190255,0.00008281745,0.00002355795,0.00001979966,0.00005673512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002542518,0.00001882747,0.01794323,0.00004542467,0.00001966672,0.0004321204,0.00003474454,0.00006040446,0.9771354,0.000147803,0.00003572131,0.003872341],"study_design_scores_gemma":[0.00003715997,0.0007635096,0.6498249,0.0000220738,0.000109422,0.007531909,0.0002120495,0.0009011197,0.3376251,0.0002893159,0.002668299,0.00001519062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951493,0.002614641,0.001229873,0.00004854041,0.00001241811,0.000008288762,0.0001833378,0.00002759053,0.0007259275],"genre_scores_gemma":[0.9985531,0.0005519331,0.0004389662,0.00001922692,0.000005575576,0.000006661569,0.0001140967,0.000004339034,0.0003060544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001044558,"threshold_uncertainty_score":0.003494442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01351742380406601,"score_gpt":0.2184450936355031,"score_spread":0.2049276698314371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}