{"id":"W4205949983","doi":"10.1038/s41598-021-04308-2","title":"Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV","year":2022,"lang":"en","type":"article","venue":"Scientific Reports","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"Common Fund; Fondation Leducq; National Human Genome Research Institute; Massachusetts General Hospital; National Science Foundation; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Haematopoiesis; Disease; Indeterminate; Inflammation; Population; Immune system; Cohort; Coronary artery disease; Human immunodeficiency virus (HIV)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002348949,0.0001221338,0.0001434971,0.0006861266,0.0003174262,0.0004366652,0.0001877928,0.0002771679,0.001539598],"category_scores_gemma":[0.001216634,0.0001242634,0.0001071889,0.0005711453,0.0002206352,0.0002149576,0.0002360147,0.0002607539,0.00006667067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008252478,"about_ca_system_score_gemma":0.00008900646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002062236,"about_ca_topic_score_gemma":0.00269481,"domain_scores_codex":[0.999836,0.00004949074,0.00001419062,0.0000459428,0.00003323142,0.00002113908],"domain_scores_gemma":[0.9995288,0.0001167442,0.0002218088,0.00003940274,0.00003949946,0.00005369371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007917933,0.00001415024,0.9950559,0.00001535432,0.00002871889,0.0001306754,0.0001283119,0.00001905174,0.00112662,0.00003321168,0.00006835619,0.003300497],"study_design_scores_gemma":[0.000003494547,0.00005092235,0.9983929,0.000008084509,0.00002278261,0.0007553619,0.0002120872,0.0001335136,0.0002451708,0.00005045461,0.0001224711,0.00000273926],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993262,0.0002990712,0.00006833293,0.00002201597,0.000002067851,0.000002704231,0.00008669627,0.000002241733,0.0001906984],"genre_scores_gemma":[0.999699,0.000123644,0.00003881981,0.00001166019,0.000005955892,0.000001589081,0.00006451272,4.465249e-7,0.00005449931],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002062236,"threshold_uncertainty_score":0.005150437,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008404378121641166,"score_gpt":0.2545839552798296,"score_spread":0.2461795771581885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}