{"id":"W4205952352","doi":"10.1186/s13287-021-02699-7","title":"Direct comparison of different therapeutic cell types susceptibility to inflammatory cytokines associated with COVID-19 acute lung injury","year":2022,"lang":"en","type":"article","venue":"Stem Cell Research & Therapy","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Institute of Circulatory and Respiratory Health; Canadian Institutes of Health Research; University of Ottawa","keywords":"Mesenchymal stem cell; Cytokine; Viability assay; Cell therapy; Paracrine signalling; Stromal cell; Medicine; Cytokine storm; Stem cell; Immunology; ARDS; Flow cytometry; Immune system; Cancer research; Cell; Biology; Cell biology; Pathology; Receptor; Internal medicine; Lung; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005713808,0.0003263745,0.000382391,0.0004463696,0.0001965299,0.0005610377,0.0001314104,0.0003389402,0.001982451],"category_scores_gemma":[0.000455604,0.0001120102,0.0003419236,0.0003550989,0.0002435352,0.000286007,0.0003023983,0.0006205983,0.0005331516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001617958,"about_ca_system_score_gemma":0.0001952189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001182258,"about_ca_topic_score_gemma":0.0001787176,"domain_scores_codex":[0.9993739,0.0001074542,0.00008355847,0.0001145187,0.0002253404,0.00009538919],"domain_scores_gemma":[0.9995505,0.0001403531,0.00007250984,0.00004721865,0.0001304137,0.00005897814],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006158479,0.0001187342,0.001737076,0.00009035016,0.00001425048,0.00004920998,0.00005970266,0.00008414681,0.9932513,0.00007236448,0.00006401961,0.003843084],"study_design_scores_gemma":[0.0000481853,0.002929047,0.01939151,0.0000162183,0.00009069317,0.0003887059,0.0001690072,0.0009154364,0.9730554,0.00007104618,0.002916861,0.000007926927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871545,0.001991511,0.007028945,0.00007201859,0.0001000235,0.000203534,0.0007623683,0.0000466176,0.002640495],"genre_scores_gemma":[0.9837166,0.001837731,0.009526781,0.0002029128,0.00005766273,0.0006351354,0.002002638,0.00002859842,0.001991874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001982451,"threshold_uncertainty_score":0.00663197,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1032953272155503,"score_gpt":0.4592446408074891,"score_spread":0.3559493135919387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}