{"id":"W4205959775","doi":"10.3389/fcell.2021.794912","title":"Genetics, Epigenetics, Cellular Immunology, and Gut Microbiota: Emerging Links With Graves’ Disease","year":2022,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Petroleum Technology Research Centre; Guizhou Science and Technology Department","keywords":"Epigenetics; Pathogenesis; Immunology; Disease; Biology; Mechanism (biology); Microbiome; Epigenome; Gut flora; Genetics; Medicine; Gene; DNA methylation; Pathology; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001527857,0.0005186221,0.0008659784,0.0002010994,0.0001872562,0.00002987812,0.0002777791,0.0006224575,0.00004549445],"category_scores_gemma":[0.00002145928,0.0004601569,0.0001197311,0.0001538824,0.0003818269,0.000002877311,0.0005823735,0.0004702178,0.000003183264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006616584,"about_ca_system_score_gemma":0.0002632357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001469693,"about_ca_topic_score_gemma":0.00001136524,"domain_scores_codex":[0.9978718,0.000187876,0.0004518081,0.0008866817,0.0000619428,0.0005399255],"domain_scores_gemma":[0.9993786,0.00002482923,0.0002168635,0.0002164014,0.00001573721,0.0001475867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009411723,0.0002018888,0.01958901,0.002119549,0.0007916571,0.00004770554,0.0001311612,0.000002005942,0.002782975,0.00001102,0.005509128,0.9687198],"study_design_scores_gemma":[0.0006044604,0.0001871396,0.0002252949,0.0001965348,0.000168322,0.000009873332,0.0003437735,0.000002074098,0.0001768806,0.00004848626,0.9973792,0.0006579995],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007799561,0.9904557,0.00009221143,0.00001930032,0.000512983,0.0004624853,0.0001958203,0.00001111999,0.0004507742],"genre_scores_gemma":[0.0006193343,0.9921435,0.003478082,0.0001242621,0.00005084908,0.0000740235,0.002851025,0.00006522101,0.0005937784],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.99187,"threshold_uncertainty_score":0.999785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007562964127003858,"score_gpt":0.2194233187588057,"score_spread":0.2118603546318019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}