{"id":"W4205977747","doi":"10.1136/bmjopen-2021-053081","title":"Camu Camu effects on microbial translocation and systemic immune activation in ART-treated people living with HIV: protocol of the single-arm non-randomised Camu Camu prebiotic pilot study (CIHR/CTN PT032)","year":2022,"lang":"en","type":"article","venue":"BMJ Open","topic":"Phytochemistry Medicinal Plant Applications","field":"Agricultural and Biological Sciences","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; McGill University Health Centre; Université Laval; Canadian Institutes of Health Research","funders":"Canadian Institutes of Health Research; Health Canada","keywords":"Medicine; Dysbiosis; Immune system; Prebiotic; Gut flora; Randomized controlled trial; Human immunodeficiency virus (HIV); Immunology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01173859,0.003770906,0.006792495,0.001666795,0.003872094,0.001890708,0.004707523,0.00607698,0.04125516],"category_scores_gemma":[0.006564443,0.002124472,0.003409913,0.001686824,0.002778497,0.001835832,0.001999395,0.003818327,0.008348287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002276052,"about_ca_system_score_gemma":0.01483281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004378309,"about_ca_topic_score_gemma":0.006778789,"domain_scores_codex":[0.9951712,0.002534867,0.000393124,0.0006073487,0.000461059,0.0008323649],"domain_scores_gemma":[0.99534,0.0005348091,0.0007029698,0.0008663763,0.0009758262,0.001579936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8477475,0.09924777,0.002142267,0.006671774,0.0005700842,0.0004279767,0.0006368185,0.0008356834,0.009678159,0.001151641,0.006589246,0.02430115],"study_design_scores_gemma":[0.5650361,0.3880261,0.01363226,0.00124026,0.0007109299,0.0001738716,0.0003682778,0.0005898404,0.002764704,0.001263661,0.02604846,0.0001454814],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.03836747,0.0004196265,0.001173541,0.0002275119,0.0002183601,0.955492,0.002639822,0.00006816529,0.001393517],"genre_scores_gemma":[0.02215781,0.0004059683,0.003345124,0.000409842,0.0001902693,0.9709135,0.0008304744,0.00001225786,0.001734695],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.04125516,"threshold_uncertainty_score":0.1380122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03053596967723445,"score_gpt":0.2779545924164021,"score_spread":0.2474186227391676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}