{"id":"W4206078260","doi":"10.1177/20543581211069225","title":"Effect of a Perioperative Hypotension-Avoidance Strategy Versus a Hypertension-Avoidance Strategy on the Risk of Acute Kidney Injury: A Clinical Research Protocol for a Substudy of the POISE-3 Randomized Clinical Trial","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Kidney Health and Disease","topic":"Hemodynamic Monitoring and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; Western University; University of Manitoba; Kingston General Hospital; Population Health Research Institute; McMaster University; London Health Sciences Centre","funders":"National Institute for Health and Care Research; Instituto de Salud Carlos III; Canadian Institutes of Health Research; Canada Research Chairs; National Center for Advancing Translational Sciences; Kidney Foundation of Canada","keywords":"Medicine; Perioperative; Randomized controlled trial; Acute kidney injury; Clinical trial; Protocol (science); Kidney disease; Anesthesia; Intensive care medicine; Internal medicine; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0207023,0.005690832,0.008337611,0.001564842,0.002661477,0.004093132,0.002479289,0.007466648,0.03860458],"category_scores_gemma":[0.03355826,0.002136247,0.007728178,0.002165035,0.002059613,0.003502808,0.001694761,0.005986513,0.006140158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003438896,"about_ca_system_score_gemma":0.007041442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002193745,"about_ca_topic_score_gemma":0.003629737,"domain_scores_codex":[0.9831312,0.01142076,0.001720103,0.001301631,0.001183562,0.00124276],"domain_scores_gemma":[0.9889473,0.0036759,0.002826224,0.001463143,0.001950862,0.00113652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9527031,0.005786553,0.0008513075,0.00883568,0.005292428,0.0001348013,0.0002026018,0.0008165528,0.0007939332,0.001550549,0.01258208,0.0104504],"study_design_scores_gemma":[0.9781806,0.009363177,0.001325209,0.001053803,0.001641308,0.00003013308,0.00004613314,0.000754531,0.0002198536,0.001354938,0.005989645,0.00004067991],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.01017718,0.001128878,0.002240926,0.0008653561,0.0008667499,0.9770836,0.004611706,0.0002422566,0.002783364],"genre_scores_gemma":[0.007492044,0.0002571,0.001864663,0.0004607611,0.0001163842,0.9886318,0.0004946301,0.00001154884,0.0006710117],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.03860458,"threshold_uncertainty_score":0.1291452,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1279134841391046,"score_gpt":0.47591747798939,"score_spread":0.3480039938502855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}