{"id":"W4206092113","doi":"10.1016/j.pan.2021.05.015","title":"Map kinase activity drives a subtype specific subset of CAFS in PDAC","year":2021,"lang":"en","type":"article","venue":"Pancreatology","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Hospital Foundation","funders":"","keywords":"Medicine; Kinase; Cancer research; Computational biology; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008503082,0.0001002619,0.0002074391,0.0000482891,0.00002002396,0.000004736541,0.00008987985,0.0001549148,0.0001425425],"category_scores_gemma":[0.00008508583,0.0001036123,0.00006195071,0.0001031025,0.0000943436,0.00000317533,0.00007293044,0.00008158047,0.00002318892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001052708,"about_ca_system_score_gemma":0.000094351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005603227,"about_ca_topic_score_gemma":0.0002319943,"domain_scores_codex":[0.9991744,0.0001451832,0.0001616226,0.0002795247,0.00005942033,0.0001798368],"domain_scores_gemma":[0.9994957,0.00001733748,0.00007021823,0.0003087489,0.00006356722,0.00004445942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001137127,0.0001164669,0.05469834,0.0000206769,0.0000195702,0.00004165772,0.00002800416,0.00000197929,0.9406686,0.0007156834,0.001841167,0.001734143],"study_design_scores_gemma":[0.0004624338,0.00007676565,0.02534969,0.000009101359,0.000005383501,0.0000287044,0.00004218319,0.000006608037,0.9295326,0.0001242016,0.04425976,0.0001025308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956281,0.002099305,0.0002339415,0.0003260723,0.0001623976,0.00008259586,0.0000193772,0.000006181955,0.001441993],"genre_scores_gemma":[0.9983451,0.0003843464,0.0004974752,0.00007464619,0.00006839995,0.00001341109,0.0001176411,0.000009957744,0.0004890145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0424186,"threshold_uncertainty_score":0.4225186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01053875115622002,"score_gpt":0.2424702507768387,"score_spread":0.2319314996206187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}