{"id":"W4206209845","doi":"10.3390/cancers14030498","title":"Therapeutic Strategies Targeting Urokinase and Its Receptor in Cancer","year":2022,"lang":"en","type":"review","venue":"Cancers","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Alleanza Contro il Cancro; Ministero della Salute","keywords":"Urokinase receptor; Medicine; Cancer; Cancer research; Receptor; Oncology; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001431438,0.0002496186,0.0004254372,0.00005696124,0.00006792358,0.00002586038,0.0001655776,0.0001852308,0.0003187948],"category_scores_gemma":[0.00001837032,0.0002294009,0.0001135488,0.0001208649,0.00002378749,0.000004782804,0.0001123726,0.0002434197,0.000003119802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003365504,"about_ca_system_score_gemma":0.001593409,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000103406,"about_ca_topic_score_gemma":0.00003460225,"domain_scores_codex":[0.9988892,0.0001180491,0.0002288774,0.0004278658,0.00009090748,0.0002451011],"domain_scores_gemma":[0.9996249,0.00001003133,0.0001374604,0.0001562847,0.00001361938,0.00005768886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003578572,0.00001545011,0.00000141117,0.006200016,0.00020236,0.00001679789,0.0000857325,0.00005206564,0.01390799,0.0004134284,0.003028392,0.9760406],"study_design_scores_gemma":[0.0001222229,0.00009417407,5.460246e-8,0.0006605327,0.00006103719,0.000003019432,0.0001014194,0.000006036968,0.002509768,0.00002290065,0.9961464,0.0002724247],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003213251,0.9982881,0.000005014314,0.000007875558,0.0004398187,0.0004445623,0.0001004852,0.000008703297,0.0003841214],"genre_scores_gemma":[0.0006090525,0.9977063,0.00001537382,0.0001103299,0.0003445901,0.0007092328,0.0002023172,0.00004597452,0.0002568367],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.993118,"threshold_uncertainty_score":0.9354696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04473687058112246,"score_gpt":0.3299883532401048,"score_spread":0.2852514826589823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}