{"id":"W4206209845","doi":"10.3390/cancers14030498","title":"Therapeutic Strategies Targeting Urokinase and Its Receptor in Cancer","year":2022,"lang":"en","type":"review","venue":"Cancers","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Alleanza Contro il Cancro; Ministero della Salute","keywords":"Urokinase receptor; Medicine; Cancer; Cancer research; Receptor; Oncology; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003135414,0.0005905041,0.0009148904,0.001486104,0.0002189979,0.0006337448,0.0005871111,0.0007915206,0.00307477],"category_scores_gemma":[0.0002630996,0.0001898671,0.0004928138,0.0008989084,0.0002917511,0.0007089498,0.0005518876,0.001683375,0.001401474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000405469,"about_ca_system_score_gemma":0.0004327515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005387751,"about_ca_topic_score_gemma":0.001293569,"domain_scores_codex":[0.9998864,0.00002216833,0.00001342586,0.00001734012,0.00004150855,0.00001918908],"domain_scores_gemma":[0.9999385,0.00002412063,0.00001144732,0.000002541985,0.00001558687,0.000007750352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001297194,0.0001302786,0.0001475343,0.01305899,0.0001020932,0.0004601708,0.00005283873,0.0005167829,0.005653123,0.004860575,0.02400086,0.950887],"study_design_scores_gemma":[0.00004313978,0.0001967031,0.000720791,0.00180665,0.0001080465,0.002290396,0.00003841135,0.0001581207,0.001333102,0.001920367,0.9913673,0.00001690445],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002457912,0.9983547,0.0001416855,0.0001951932,0.0001577518,0.000006362637,0.00001326753,0.000007315281,0.0008779076],"genre_scores_gemma":[0.001791178,0.9967102,0.0002242871,0.000233171,0.0001476704,0.00001076244,0.00004132333,0.000001711888,0.000839621],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00307477,"threshold_uncertainty_score":0.01028609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04473687058112246,"score_gpt":0.3299883532401048,"score_spread":0.2852514826589823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}