{"id":"W4206211052","doi":"10.1002/jcsm.12909","title":"C/EBPβ promotes the expression of atrophy‐inducing factors by tumours and is a central regulator of cancer cachexia","year":2022,"lang":"en","type":"article","venue":"Journal of Cachexia Sarcopenia and Muscle","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; King Saud University; Cancer Research Society","keywords":"Cachexia; Endocrinology; Gene knockdown; Skeletal muscle; Internal medicine; Biology; Muscle atrophy; Cancer research; Atrophy; Transcription factor; Cancer; Medicine; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001515566,0.0004068711,0.0002600781,0.0002980352,0.0001885593,0.0002626189,0.0001381811,0.0001929952,0.001512215],"category_scores_gemma":[0.0000800945,0.0001260497,0.0002649793,0.0001815846,0.0003341075,0.0001370816,0.000228618,0.0006711265,0.0005470802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003250538,"about_ca_system_score_gemma":0.0002718216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007831913,"about_ca_topic_score_gemma":0.000797865,"domain_scores_codex":[0.9998834,0.00001097421,0.000009130172,0.00001908747,0.00004571159,0.00003156605],"domain_scores_gemma":[0.9998698,0.00001210797,0.00003479345,0.00001136126,0.0000222,0.00004976024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005780785,0.00001521428,0.0002024014,0.00003052937,0.000003631756,0.00003498294,0.000008400534,0.00001871747,0.9990703,0.00003980148,0.00003767459,0.000480661],"study_design_scores_gemma":[0.00002664171,0.000333359,0.01575937,0.0000143135,0.00001669253,0.0004842741,0.00004288695,0.0005343186,0.9782473,0.00005394702,0.004482466,0.000004506791],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866742,0.006710906,0.002370767,0.0002139971,0.00004690374,0.000048883,0.0006895026,0.0001538783,0.003090868],"genre_scores_gemma":[0.989528,0.002669579,0.001655355,0.00009940356,0.00001970417,0.0000751115,0.001145376,0.00003426781,0.004773173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001512215,"threshold_uncertainty_score":0.005058885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007162490726119531,"score_gpt":0.2402081406664919,"score_spread":0.2330456499403724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}