{"id":"W4206224480","doi":"10.3390/v14010088","title":"Influenza A Virus Infection Activates NLRP3 Inflammasome through Trans-Golgi Network Dispersion","year":2022,"lang":"en","type":"article","venue":"Viruses","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Inflammasome; Innate immune system; Cell biology; Influenza A virus; Pyroptosis; AIM2; Nigericin; Immune system; Virus; Biology; Virology; Chemistry; Inflammation; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001116306,0.0002849588,0.0001654368,0.0001286792,0.0001383188,0.0002327421,0.0001336484,0.000343727,0.0003842331],"category_scores_gemma":[0.0000760443,0.000114017,0.0003368641,0.0001056147,0.0001951867,0.0003158904,0.0002697462,0.0004170088,0.0001315237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002948343,"about_ca_system_score_gemma":0.0001557937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004609254,"about_ca_topic_score_gemma":0.0004590787,"domain_scores_codex":[0.9999088,0.00002025394,0.00001245641,0.00002164876,0.0000159645,0.00002079838],"domain_scores_gemma":[0.9999497,0.000004352137,0.00002262576,0.000006850934,0.000005359977,0.00001107649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008364813,0.000009201299,0.0002872972,0.0000204501,0.000005135375,0.00008500317,0.00001207682,0.00004126942,0.99898,0.0001353085,0.00001397469,0.0003267445],"study_design_scores_gemma":[0.00002870466,0.000301318,0.0110633,0.0000136846,0.00002007569,0.001122621,0.00007117281,0.002413875,0.982631,0.0003139256,0.002010092,0.00001018501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947987,0.001335324,0.002898993,0.00008217477,0.00002054418,0.00002213295,0.0001418736,0.00003713878,0.000663173],"genre_scores_gemma":[0.9971526,0.0005594977,0.001654971,0.00003758879,0.000003477126,0.00001325643,0.0001411035,0.000005612093,0.0004318219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004609254,"threshold_uncertainty_score":0.002139211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0180544333513998,"score_gpt":0.264632376304878,"score_spread":0.2465779429534782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}