{"id":"W4206224480","doi":"10.3390/v14010088","title":"Influenza A Virus Infection Activates NLRP3 Inflammasome through Trans-Golgi Network Dispersion","year":2022,"lang":"en","type":"article","venue":"Viruses","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Inflammasome; Innate immune system; Cell biology; Influenza A virus; Pyroptosis; AIM2; Nigericin; Immune system; Virus; Biology; Virology; Chemistry; Inflammation; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001660596,0.0002287223,0.000176399,0.0000508401,0.0005585712,0.0000374308,0.0002118751,0.0001153414,0.0003671062],"category_scores_gemma":[0.00003686473,0.0002352855,0.0001644236,0.0002678616,0.00007787705,0.00003183706,0.0002271233,0.000224057,0.00003326613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003575502,"about_ca_system_score_gemma":0.00006649329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003910611,"about_ca_topic_score_gemma":0.0001041981,"domain_scores_codex":[0.9986187,0.0001437466,0.0002683955,0.0003697954,0.0002020187,0.0003974093],"domain_scores_gemma":[0.9994237,0.00001746259,0.0001117919,0.0003660703,0.00003756534,0.00004334176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000552221,0.0001303871,0.01913952,0.0000185261,0.0001337203,0.000004047675,0.0003737663,0.01181193,0.9585218,0.0001944923,0.006150024,0.002969574],"study_design_scores_gemma":[0.000657366,0.0003824481,0.003406171,0.000007372108,0.00002555156,0.0000056062,0.0001366927,0.00002120746,0.2873444,0.0001897646,0.7075383,0.0002850992],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945923,0.002845376,0.0003122082,0.00007803561,0.0004562054,0.0002575752,0.00003237426,0.0000592613,0.001366628],"genre_scores_gemma":[0.9943967,0.001603018,0.00008651034,0.002929838,0.0003839637,0.000155379,0.0001648053,0.00005302673,0.0002267305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7013883,"threshold_uncertainty_score":0.9594663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0180544333513998,"score_gpt":0.264632376304878,"score_spread":0.2465779429534782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}