{"id":"W4206295695","doi":"10.1002/9780470292549.ch29","title":"Preclinical Safety Evaluation of Immunotoxins","year":2007,"lang":"en","type":"other","venue":"","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Viventia Bio (Canada)","funders":"","keywords":"Immunotoxin; Medicine; Immunology; Antibody; Monoclonal antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.002156549,0.0003195848,0.0006256622,0.0004544302,0.00004900019,0.0000049004,0.0003828239,0.001484703,0.1555672],"category_scores_gemma":[0.0001998756,0.0002703407,0.0002565469,0.0001582194,0.0002188879,0.00002582895,0.0001186616,0.0004750987,0.002803806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006409799,"about_ca_system_score_gemma":0.0002181265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002910443,"about_ca_topic_score_gemma":0.0001296237,"domain_scores_codex":[0.9979938,0.0003555896,0.0007300154,0.0004058587,0.0001572864,0.0003574704],"domain_scores_gemma":[0.9984428,0.0001255917,0.0005020997,0.0007658537,0.0001459137,0.00001771878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003164792,0.0006354646,0.00005648195,0.00008385204,0.001547549,0.000001444364,0.0001086717,0.000002026735,0.175091,0.01497358,0.6683302,0.1388532],"study_design_scores_gemma":[0.002345698,0.0001968032,0.0003487491,0.0001880115,0.0003202376,0.000009916345,0.00006230696,0.000004399892,0.04377174,0.0001750593,0.9522478,0.000329278],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.0001782588,0.01450435,0.001372052,0.00002068307,0.00258823,0.0009575967,0.0001506716,0.0002050648,0.9800231],"genre_scores_gemma":[0.008858894,0.0006374661,0.0008056618,0.00008612162,0.00009421423,0.00002761794,0.0004617274,0.0003218167,0.9887065],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.2839176,"threshold_uncertainty_score":0.9999749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03892871690497027,"score_gpt":0.3289345707442086,"score_spread":0.2900058538392383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}