{"id":"W4206331989","doi":"10.1177/23978473211061428","title":"Safety assessment of purine nucleosidase from <i>Aspergillus luchuensis</i>","year":2021,"lang":"en","type":"article","venue":"Toxicology Research and Application","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Intertek (Canada)","funders":"","keywords":"Purine; Purine analogue; Chemistry; Purine metabolism; Ames test; Pharmacology; Biochemistry; Food science; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003764915,0.00008693476,0.0001439128,0.00003790782,0.0001108941,0.00001487024,0.000156172,0.0001881346,0.0000737553],"category_scores_gemma":[0.0001347694,0.00008310902,0.00003955099,0.0001898086,0.0003683866,0.000002635865,0.0003798321,0.0002099401,0.000007589497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001760576,"about_ca_system_score_gemma":0.0001931448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004035023,"about_ca_topic_score_gemma":0.00006590301,"domain_scores_codex":[0.998673,0.0001666849,0.0001846447,0.0004434852,0.0002378201,0.0002943407],"domain_scores_gemma":[0.9990248,0.0000671559,0.00003584155,0.0004071636,0.0003182497,0.0001467998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009545329,0.0002202607,0.00111734,0.00001975299,0.00003907026,0.000006118027,0.000008292212,0.000001634722,0.987964,0.001635424,0.001185574,0.007707071],"study_design_scores_gemma":[0.0005452789,0.0002695056,0.008713896,0.000007172877,0.000005473086,0.000009752841,0.00004043308,0.0001171703,0.9474947,0.00118982,0.04152369,0.00008310956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891924,0.001502121,0.002779684,0.001318201,0.00001566439,0.0002588361,0.00006485973,0.00000729429,0.004860977],"genre_scores_gemma":[0.9961573,0.001127573,0.001212605,0.000118466,0.00009627334,0.00007552739,0.0004991838,0.00001217837,0.0007009151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04046931,"threshold_uncertainty_score":0.3389088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02006289439194863,"score_gpt":0.362525149919563,"score_spread":0.3424622555276144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}