{"id":"W4206349574","doi":"10.7554/elife.68174.sa2","title":"Author response: Non-nucleoside reverse transcriptase inhibitor-based combination antiretroviral therapy is associated with lower cell-associated HIV RNA and DNA levels compared to protease inhibitor-based therapy","year":2021,"lang":"en","type":"peer-review","venue":"","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Reverse transcriptase; Reverse-transcriptase inhibitor; Nucleoside Reverse Transcriptase Inhibitor; Protease inhibitor (pharmacology); Nucleoside; Regimen; RNA; Viral load; Virology; DNA; Antiretroviral therapy; Human immunodeficiency virus (HIV); Medicine; Biology; Internal medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002914213,0.0004277032,0.0006242798,0.0004281529,0.0002889883,0.0008270603,0.0005402028,0.001181025,0.04926666],"category_scores_gemma":[0.02315245,0.0001587149,0.0006473884,0.0006849503,0.0002842864,0.0005234306,0.00041849,0.0008436763,0.007619389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002308102,"about_ca_system_score_gemma":0.0005385107,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000462969,"about_ca_topic_score_gemma":0.0006139776,"domain_scores_codex":[0.9971131,0.001359777,0.0002722646,0.0005366004,0.0005268277,0.0001913302],"domain_scores_gemma":[0.9876539,0.006326502,0.002575775,0.0005330597,0.002365889,0.0005448922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004195102,0.0002167979,0.382176,0.001918633,0.0008233243,0.0005048446,0.0003136213,0.001158906,0.0007784307,0.0008853749,0.5288531,0.07817587],"study_design_scores_gemma":[0.003043564,0.003600653,0.7165536,0.002368349,0.001211078,0.00340811,0.002694645,0.00520745,0.003884444,0.006235703,0.2515261,0.000266295],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.59858,0.0151402,0.01007288,0.1833011,0.05909017,0.001068749,0.06535308,0.001699221,0.06569459],"genre_scores_gemma":[0.8547003,0.004232961,0.003743673,0.0699697,0.009098609,0.0007300692,0.01261036,0.0003297493,0.04458453],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.04926666,"threshold_uncertainty_score":0.1648134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04032031671141035,"score_gpt":0.2994022982783918,"score_spread":0.2590819815669815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}